Antiretroviral drug concentrations in semen of HIV-infected men: differential penetration of indinavir, ritonavir and saquinavir

Variable drug penetration of antiretroviral drugs into the genital tract may contribute to the differential evolution of HIV and the emergence of drug resistance. This, in turn, may have an impact on the sexual transmission of resistant HIV in patients treated with antiretroviral drugs. We have meas...

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Veröffentlicht in:	Journal of antimicrobial chemotherapy 2001-09, Vol.48 (3), p.351-354
Hauptverfasser:	Taylor, Stephen, Back, David J., Drake, Susan M., Workman, Judith, Reynolds, Helen, Gibbons, Sara E., White, David J., Pillay, Deenan
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Anti-HIV Agents - pharmacokinetics Antibiotics. Antiinfectious agents. Antiparasitic agents Antiviral agents Biological and medical sciences HIV Infections - metabolism HIV Protease Inhibitors - pharmacokinetics Human immunodeficiency virus 1 Humans Indinavir - pharmacokinetics Male Medical sciences Middle Aged Pharmacology. Drug treatments Ritonavir - pharmacokinetics Saquinavir - pharmacokinetics Semen - metabolism
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