Exercise Down-Regulates Hepatic Fatty Acid Synthase in Streptozotocin-Treated Rats

An acute bout of prolonged exercise has been shown to decrease hepatic fatty acid synthase (FAS) mRNA and activity induced by high carbohydrate diets. The purpose of the current study was to examine the role of insulin in this exercise down-regulation of FAS. Sixty-four male Wistar rats were randoml...

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Veröffentlicht in:	The Journal of nutrition 2001-09, Vol.131 (9), p.2252-2259
Hauptverfasser:	Fiebig, Russell G., Hollander, John M., Ji, Li Li
Format:	Artikel
Sprache:	eng
Schlagworte:	animal models Animals binding proteins Biological and medical sciences blood glucose Blood Glucose - analysis Body Weight corn starch diabetes mellitus Diabetes Mellitus, Experimental - enzymology Diabetes Mellitus, Experimental - pathology Diabetes. Impaired glucose tolerance diet dietary carbohydrate Down-Regulation Endocrine pancreas. Apud cells (diseases) Endocrinopathies enzyme activity Etiopathogenesis. Screening. Investigations. Target tissue resistance Exercise fatty acid synthase Fatty Acid Synthases - genetics Fatty Acid Synthases - metabolism Fatty acids fructose glucagon Glucagon - blood human diseases human nutrition Insulin Insulin - blood liver Liver - enzymology Male Medical sciences messenger RNA Motor Activity - physiology nuclear binding proteins Rats Rats, Wistar Reference Values Ribonucleic acid RNA RNA, Messenger - metabolism Rodents transcription factor transcription factors Transcription Factors - metabolism
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