Bioavailability studies of oral dosage forms containing levodopa and carbidopa using column-switching chromatography followed by electrochemical detection

A reliable multi-dimensional column chromatographic method employing amperometric detection using a carbon fibre microelectrode procedure was used for monitoring the plasma profiles and to evaluate the pharmacokinetics and bioavailability of levodopa (L-dopa) and carbidopa (C-dopa), after ingestion...

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Veröffentlicht in:	Analyst (London) 2000-01, Vol.125 (3), p.439-445
Hauptverfasser:	SAGAR, K. A, SMYTH, M. R
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Analysis Antiparkinson Agents - pharmacokinetics Biological and medical sciences Biological Availability Carbidopa - pharmacokinetics Chromatography, High Pressure Liquid - methods Dopamine Agents - pharmacokinetics Female General pharmacology Humans Levodopa - pharmacokinetics Male Medical sciences Pharmacology. Drug treatments
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