Association of tumour site and sex with survival benefit from adjuvant chemotherapy in colorectal cancer

Adjuvant chemotherapy can improve 5-year survival in Dukes' C colorectal carcinoma. Improved selection of patients who will respond to adjuvant treatments is required. We investigated whether site of tumour origin, sex, and presence of microsatellite instability (MSI) phenotype were associated...

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Veröffentlicht in:	The Lancet (British edition) 2000-05, Vol.355 (9217), p.1745-1750
Hauptverfasser:	Elsaleh, Hany, Joseph, David, Grieu, Fabienne, Zeps, Nik, Spry, Nigel, Iacopetta, Barry
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Antineoplastic agents Biological and medical sciences Chemotherapy Chemotherapy, Adjuvant Colorectal cancer Colorectal carcinoma Colorectal Neoplasms - drug therapy Colorectal Neoplasms - genetics Colorectal Neoplasms - mortality Colorectal Neoplasms - pathology Combined treatments (chemotherapy of immunotherapy associated with an other treatment) Female Follow-Up Studies Humans Male Medical research Medical sciences Microsatellite Repeats Pharmacology. Drug treatments Sex Factors Survival Rate Tumors
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