Influences of alkyl group chain length and polar head group on chemical skin permeation enhancement

Previous investigations in our laboratory on the influence of the n‐alkanols and the 1‐alkyl‐2‐pyrrolidones as skin permeation enhancers for steroid molecules as permeants demonstrated that the enhancer potencies (based on aqueous concentration values) of these two homologous series were the same wh...

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Veröffentlicht in:	Journal of pharmaceutical sciences 2001-08, Vol.90 (8), p.1143-1153
Hauptverfasser:	Warner, Kevin S., Li, S.Kevin, Higuchi, William I.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkanes - chemistry Alkanes - pharmacology Animals Biological and medical sciences enhancer mechanism General pharmacology Medical sciences Mice Mice, Hairless Permeability permeation enhancers Pharmaceutical technology. Pharmaceutical industry Pharmacology. Drug treatments Skin Absorption - drug effects stratum corneum Structure-Activity Relationship transdermal
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