A submembranous matrix of proteoglycans on zymogen granule membranes is involved in granule formation in rat pancreatic acinar cells

The secretory lectin ZG16p mediated the binding of aggregated zymogens to the granule membrane in pancreatic acinar cells. Using a recently established in vitro condensation-sorting assay, we now show that pretreatment of zymogen granule membranes (ZGM) with either sodium bicarbonate at pH 10 or wit...

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Veröffentlicht in:	Journal of cell science 2000-06, Vol.113 ( Pt 12) (12), p.2233-2242
Hauptverfasser:	Schmidt, K, Dartsch, H, Linder, D, Kern, H F, Kleene, R
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cytoplasmic Granules - metabolism Cytoplasmic Granules - ultrastructure Enzyme Precursors - metabolism Intracellular Membranes - metabolism Male Microscopy, Electron Pancreas - metabolism Pancreas - ultrastructure Proteoglycans - metabolism Rats Rats, Wistar
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