Bispecific and bifunctional single chain recombinant antibodies

Bispecific and bifunctional monoclonal antibodies as second generation monoclonals, produced by conventional chemical or somatic methods, have proved useful in the immunodiagnosis and immunotherapy of cancer and other diseases. Recombinant antibodies produced by genetic engineering techniques have a...

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Veröffentlicht in:	Biomolecular engineering 2001-09, Vol.18 (2), p.31-40
Hauptverfasser:	Kriangkum, Jitra, Xu, Biwen, Nagata, Les P., Fulton, R.Elaine, Suresh, Mavanur R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bifunctional Biotechnology - methods Bispecific antibodies Blotting, Western Humans Immunoglobulin Fragments - chemistry Immunoglobulin Fragments - metabolism Immunotherapy Mice Models, Molecular Neoplasms - diagnosis Protein Structure, Tertiary Recombinant antibodies Recombinant Proteins - chemistry Recombinant Proteins - metabolism scFv
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