Water Vapor Adsorption Properties of Amorphous Cefditoren Pivoxil Evaluated by Adsorption Isotherms and Microcalorimetry

Water vapor adsorption of ground cefditoren pivoxil was studied. The amount of water adsorbed increased with a decrease in the crystallinity of cefditoren pivoxil. It was found from the microcalorimetric measurements that the differential heat of water vapor adsorption at 1.5% adsorbed water increas...

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Veröffentlicht in:	Drug development and industrial pharmacy 2000-01, Vol.26 (6), p.643-649
Hauptverfasser:	Ohta, Masato, Tozuka, Yuichi, Oguchi, Toshio, Yamamoto, Keiji
Format:	Artikel
Sprache:	eng
Schlagworte:	Amorphous Anti-Bacterial Agents - chemistry Calorimetry Cefditoren pivoxil Cephalosporins - chemistry Grinding Heat of adsorption Microcalorimetry Spectrophotometry, Infrared Volatilization Water - chemistry Water vapor adsorption isotherm Wettability
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