Ru-Catalyzed Cyclocarbonylation of α- and β-Allenic Sulfonamides:  Synthesis of γ- and δ-Unsaturated Lactams

Ru-Catalyzed Cyclocarbonylation of α- and β-Allenic Sulfonamides:  Synthesis of γ- and δ-Unsaturated Lactams

The Ru-catalyzed cyclocarbonylation of α- or β-allenic sulfonamides in the presence of Ru3(CO)12 (1 mol %) and Et3N (1.5 equiv) under CO atmosphere (20 atm) in dioxane at 100 °C for 9 h gave heterocyclic γ- and δ-unsaturated lactams in good yields.

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Bibliographische Detailangaben
Veröffentlicht in:Organic letters 2001-09, Vol.3 (18), p.2851-2853
Hauptverfasser: Kang, Suk-Ku, Kim, Kwang-Jin, Yu, Chan-Mo, Hwang, Jeong-Wook, Do, Young-Kyu
Format: Artikel
Sprache:eng
Schlagworte:
beta-Lactams - chemical synthesis
beta-Lactams - chemistry
Catalysis
Cyclization
Ruthenium - chemistry
Sulfonamides - chemistry
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Zusammenfassung:The Ru-catalyzed cyclocarbonylation of α- or β-allenic sulfonamides in the presence of Ru3(CO)12 (1 mol %) and Et3N (1.5 equiv) under CO atmosphere (20 atm) in dioxane at 100 °C for 9 h gave heterocyclic γ- and δ-unsaturated lactams in good yields.
ISSN:1523-7060
1523-7052
DOI:10.1021/ol016281c