An anti-apoptotic role for NGF receptors in human rhabdomyosarcoma

The expression and biological function of Nerve Growth Factor (NGF) receptors was studied in a panel of rhabdomyosarcoma cell lines derived from embryonal and alveolar histotype. All the cell lines expressed both the high affinity receptor TrkA and the low affinity receptor p75NTR. Treatment with ex...

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Veröffentlicht in:	European journal of cancer (1990) 2001-09, Vol.37 (13), p.1719-1725
Hauptverfasser:	Astolfi, A., Nanni, P., Landuzzi, L., Ricci, C., Nicoletti, G., Rossi, I., Lollini, P.-L., De Giovanni, C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Apoptosis - physiology Biological and medical sciences Diseases of the osteoarticular system Human rhabdomyosarcoma Humans Medical sciences Neoplasm Proteins - metabolism Nerve Growth Factors - metabolism NGF p75NTR Receptor, Nerve Growth Factor - metabolism Receptor, Nerve Growth Factor - physiology Receptor, trkA - metabolism Receptors, Nerve Growth Factor - metabolism rhabdomyosarcoma Rhabdomyosarcoma - metabolism Rhabdomyosarcoma - pathology RNA, Messenger - metabolism TrkA Tumor Cells, Cultured Tumors of striated muscle and skeleton
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