Inhibition of the Arp2/3 complex-nucleated actin polymerization and branch formation by tropomyosin

The actin filament network immediately under the plasma membrane at the leading edge of rapidly moving cells consists of short, branched filaments, while those deeper in the cortex are much longer and are rarely branched [1–3]. Nucleation by the Arp2/3 complex activated by membrane-bound factors (Rh...

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Veröffentlicht in:	Current biology 2001-08, Vol.11 (16), p.1300-1304
Hauptverfasser:	Blanchoin, Laurent, Pollard, Thomas D, Hitchcock-DeGregori, Sarah E
Format:	Artikel
Sprache:	eng
Schlagworte:	Actin Cytoskeleton - metabolism Actin-Related Protein 2 Actins - metabolism Animals Cytoskeletal Proteins Humans Kinetics Microfilament Proteins - metabolism Microscopy, Fluorescence Muscle, Skeletal - chemistry Protein Isoforms - metabolism Recombinant Proteins - genetics Recombinant Proteins - metabolism Tropomyosin - genetics Tropomyosin - metabolism
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