Nature of linkage between the cationic headgroup and cholesteryl skeleton controls gene transfection efficiency

Three novel cationic cholesterol derivatives with different modes of linkage between the cationic headgroup and the cholesteryl backbone have been synthesized and used as mixtures with 1,2-dioleoyl- L-α-glycero-3-phosphatidyl ethanolamine (DOPE) for liposome-mediated gene transfection. A pronounced...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	FEBS letters 2000-05, Vol.473 (3), p.341-344
Hauptverfasser:	Ghosh, Yamuna Krishnan, Visweswariah, Sandhya S., Bhattacharya, Santanu
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cationic cholesterol amphiphile Cationic liposome Cations - chemistry Cholesterol - analogs & derivatives Cholesterol - chemistry COS Cells DNA transfection Ether linkage Genes, Reporter Glycerophospholipids - chemical synthesis Glycerophospholipids - metabolism Liposomes - chemistry Luciferases - genetics Phosphatidylethanolamines Transfection - methods
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!