The effect of ryanodine on isometric tension development in isolated ventricular trabeculae from Pacific mackerel ( Scomber japonicus)

An isometric muscle preparation was used to study the inhibitory effect of ryanodine on contractile function in isolated ventricular trabeculae of the Pacific mackerel ( Scomber japonicus). Ryanodine (an inhibitor of sarcoplasmic reticulum (SR) function) caused a 20% reduction in peak tension at 20°...

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Veröffentlicht in:	Comparative biochemistry and physiology. Part A, Molecular & integrative physiology Molecular & integrative physiology, 2000-03, Vol.125 (3), p.331-341
Hauptverfasser:	Shiels, H.A., Farrell, A.P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenaline Animals Calcium - metabolism Cardiac physiology Epinephrine - pharmacology Fishes - physiology Force-frequency Heart Ventricles - drug effects Heart Ventricles - metabolism In Vitro Techniques Ion Transport Isometric Contraction - drug effects Marine Pacific mackerel ( Scomber japonicus) Ryanodine Ryanodine - pharmacology Sarcoplasmic reticulum (SR) Scomber japonicus Scombrid physiology Temperature Ventricle Ventricular Function
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