GANGLIOSIDE-MEDIATED METABOLIC SYNCHRONIZATION OF PROTEIN SYNTHESIS ACTIVITY IN CULTURED HEPATOCYTES

An ultradian oscillation of protein synthesis was detected by synchronization of metabolic activity in rat hepatocyte cultures. This oscillation occurs in dense cultures in fresh medium, but not in sparse ones. Metabolic synchronization of sparse cultures, however, was initiated by conditioned mediu...

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Veröffentlicht in:	Cell biology international 2000-04, Vol.24 (4), p.211-222
Hauptverfasser:	Brodsky, Vsevolod Y., Nechaeva, Natalia V., Zvezdina, Natalia D., Novikova, Tatjana E., Gvasava, Inna G., Fateeva, Valentina I., Prokazova, Nina V., Golovanova, Natalia K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Activity Cycles Animals Antibodies Cell Communication Cell Count Cells, Cultured Culture Media, Conditioned Culture Media, Serum-Free G(M1) Ganglioside - pharmacology G(M1) Ganglioside - physiology gangliosides Gangliosides - pharmacology Gangliosides - physiology hepatocyte culture Humans immunocytochemistry Kinetics Liver - cytology Liver - metabolism metabolic synchronization Protein Biosynthesis protein synthesis ultradian rhythms
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