MCP-1 and MIP-2 levels during Echinococcus granulosus infections in mice
Ten BALB/c mice were infected with the cestode Echinococcus granulosus. After the infection, serum was collected at different periods of time and monocyte chemotactic protein-1 (MCP-1) and macrophage inflammatory protein-2 (MIP-2) were determined. The level of MCP-1 increased from 290±12 pg ml-1 (me...
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| Veröffentlicht in: | Journal of helminthology 2001-06, Vol.75 (2), p.205-208 |
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| container_title | Journal of helminthology |
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| creator | Theodorides, Y. Frydas, S. Rallis, T. Adamama-Moraitou, K. Papazahariadou, R. Batzios, C. Conti, P. |
| description | Ten BALB/c mice were infected with the cestode Echinococcus granulosus. After the infection, serum was collected at different periods of time and monocyte chemotactic protein-1 (MCP-1) and macrophage inflammatory protein-2 (MIP-2) were determined. The level of MCP-1 increased from 290±12 pg ml-1 (mean±SD) at day 20 post infection (p.i.), to a maximum of 820±23 pg ml-1 on day 60 p.i., then decreased to 460±12.6 pg ml-1 on day 130 p.i. A second peak was observed at day 150 p.i. In addition, MIP-2 was detectable in serum as late as day 100 p.i. The highest level (100±11 pg ml-1) was observed on day 130 p.i., and decreased thereafter. Serum from noninfected animals (controls) contained no detectable levels of either MCP-1 or MIP-2. However, MCP-1 and MIP-2 appear to be implicated in E. granulosus infections, but their exact role during the disease is under determination. |
| doi_str_mv | 10.1079/JOH200139 |
| format | Article |
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After the infection, serum was collected at different periods of time and monocyte chemotactic protein-1 (MCP-1) and macrophage inflammatory protein-2 (MIP-2) were determined. The level of MCP-1 increased from 290±12 pg ml-1 (mean±SD) at day 20 post infection (p.i.), to a maximum of 820±23 pg ml-1 on day 60 p.i., then decreased to 460±12.6 pg ml-1 on day 130 p.i. A second peak was observed at day 150 p.i. In addition, MIP-2 was detectable in serum as late as day 100 p.i. The highest level (100±11 pg ml-1) was observed on day 130 p.i., and decreased thereafter. Serum from noninfected animals (controls) contained no detectable levels of either MCP-1 or MIP-2. However, MCP-1 and MIP-2 appear to be implicated in E. granulosus infections, but their exact role during the disease is under determination.</description><identifier>ISSN: 0022-149X</identifier><identifier>EISSN: 1475-2697</identifier><identifier>DOI: 10.1079/JOH200139</identifier><identifier>PMID: 11520447</identifier><identifier>CODEN: JOHLAT</identifier><language>eng</language><publisher>Cambridge, UK: Cambridge University Press</publisher><subject>Animals ; Antibodies, Monoclonal ; Biological and medical sciences ; Chemokine CCL2 - blood ; Chemokine CXCL2 ; Chemokines - blood ; Disease Progression ; Echinococcosis, Hepatic - immunology ; Echinococcosis, Hepatic - veterinary ; Enzyme-Linked Immunosorbent Assay - methods ; Experimental helminthic diseases. Models ; Helminthic diseases ; Infectious diseases ; Medical sciences ; Mice ; Mice, Inbred BALB C ; Parasitic diseases ; Regression Analysis ; Time Factors</subject><ispartof>Journal of helminthology, 2001-06, Vol.75 (2), p.205-208</ispartof><rights>Copyright © Cambridge University Press 2001</rights><rights>2002 INIST-CNRS</rights><rights>Cambridge University Press</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c412t-371db7df4053dda224621dc07de8c01e3093cfefe0f582d77c04407fbc1b5aee3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.cambridge.org/core/product/identifier/S0022149X0100030X/type/journal_article$$EHTML$$P50$$Gcambridge$$H</linktohtml><link.rule.ids>164,309,310,314,776,780,785,786,23910,23911,25119,27903,27904,55606</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=14059892$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11520447$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Theodorides, Y.</creatorcontrib><creatorcontrib>Frydas, S.</creatorcontrib><creatorcontrib>Rallis, T.</creatorcontrib><creatorcontrib>Adamama-Moraitou, K.</creatorcontrib><creatorcontrib>Papazahariadou, R.</creatorcontrib><creatorcontrib>Batzios, C.</creatorcontrib><creatorcontrib>Conti, P.</creatorcontrib><title>MCP-1 and MIP-2 levels during Echinococcus granulosus infections in mice</title><title>Journal of helminthology</title><addtitle>J. Helminthol</addtitle><description>Ten BALB/c mice were infected with the cestode Echinococcus granulosus. After the infection, serum was collected at different periods of time and monocyte chemotactic protein-1 (MCP-1) and macrophage inflammatory protein-2 (MIP-2) were determined. The level of MCP-1 increased from 290±12 pg ml-1 (mean±SD) at day 20 post infection (p.i.), to a maximum of 820±23 pg ml-1 on day 60 p.i., then decreased to 460±12.6 pg ml-1 on day 130 p.i. A second peak was observed at day 150 p.i. In addition, MIP-2 was detectable in serum as late as day 100 p.i. The highest level (100±11 pg ml-1) was observed on day 130 p.i., and decreased thereafter. Serum from noninfected animals (controls) contained no detectable levels of either MCP-1 or MIP-2. However, MCP-1 and MIP-2 appear to be implicated in E. granulosus infections, but their exact role during the disease is under determination.</description><subject>Animals</subject><subject>Antibodies, Monoclonal</subject><subject>Biological and medical sciences</subject><subject>Chemokine CCL2 - blood</subject><subject>Chemokine CXCL2</subject><subject>Chemokines - blood</subject><subject>Disease Progression</subject><subject>Echinococcosis, Hepatic - immunology</subject><subject>Echinococcosis, Hepatic - veterinary</subject><subject>Enzyme-Linked Immunosorbent Assay - methods</subject><subject>Experimental helminthic diseases. Models</subject><subject>Helminthic diseases</subject><subject>Infectious diseases</subject><subject>Medical sciences</subject><subject>Mice</subject><subject>Mice, Inbred BALB C</subject><subject>Parasitic diseases</subject><subject>Regression Analysis</subject><subject>Time Factors</subject><issn>0022-149X</issn><issn>1475-2697</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2001</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><recordid>eNpl0F1rFDEUBuAgFrtWL_wDMggKUsaek8xsNpeytN1Kl9ai4F3IJCdr6ny0yU7Rf2_KDl3QqxzIw-E9L2NvED4hSHXy5WrFAVCoZ2yGlaxLPlfyOZsBcF5ipX4cspcp3QKAQF6_YIeINYeqkjO2Wi-vSyxM74r1xXXJi5YeqE2FG2PoN8Wp_Rn6wQ7WjqnYRNOP7ZDyGHpPdhuG_nEsumDpFTvwpk30enqP2Pez02_LVXl5dX6x_HxZ2gr5thQSXSOdr6AWzhnOqzlHZ0E6WlhAEqCE9eQJfL3gTkqbc4L0jcWmNkTiiH3Y7b2Lw_1Iaau7kCy1relpGJOWiBxkjRm--wfeDmPsczbNUVQKchUZfdwhG4eUInl9F0Nn4h-NoB-71U_dZvt2Wjg2Hbm9nMrM4P0ETLKm9bkuG9Le5ZvVQvHsyp0LaUu_n_5N_KXnUshaz8-_6jUqXPL1jV5kfzyFNF0Tg9vQ_pT_Y_4FUpebMw</recordid><startdate>20010601</startdate><enddate>20010601</enddate><creator>Theodorides, Y.</creator><creator>Frydas, S.</creator><creator>Rallis, T.</creator><creator>Adamama-Moraitou, K.</creator><creator>Papazahariadou, R.</creator><creator>Batzios, C.</creator><creator>Conti, P.</creator><general>Cambridge University Press</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QG</scope><scope>7SN</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8C1</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ATCPS</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>F1W</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>H95</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>L.G</scope><scope>M0K</scope><scope>M0S</scope><scope>M1P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>20010601</creationdate><title>MCP-1 and MIP-2 levels during Echinococcus granulosus infections in mice</title><author>Theodorides, Y. ; Frydas, S. ; Rallis, T. ; Adamama-Moraitou, K. ; Papazahariadou, R. ; Batzios, C. ; Conti, P.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c412t-371db7df4053dda224621dc07de8c01e3093cfefe0f582d77c04407fbc1b5aee3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2001</creationdate><topic>Animals</topic><topic>Antibodies, Monoclonal</topic><topic>Biological and medical sciences</topic><topic>Chemokine CCL2 - blood</topic><topic>Chemokine CXCL2</topic><topic>Chemokines - blood</topic><topic>Disease Progression</topic><topic>Echinococcosis, Hepatic - immunology</topic><topic>Echinococcosis, Hepatic - veterinary</topic><topic>Enzyme-Linked Immunosorbent Assay - methods</topic><topic>Experimental helminthic diseases. Models</topic><topic>Helminthic diseases</topic><topic>Infectious diseases</topic><topic>Medical sciences</topic><topic>Mice</topic><topic>Mice, Inbred BALB C</topic><topic>Parasitic diseases</topic><topic>Regression Analysis</topic><topic>Time Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Theodorides, Y.</creatorcontrib><creatorcontrib>Frydas, S.</creatorcontrib><creatorcontrib>Rallis, T.</creatorcontrib><creatorcontrib>Adamama-Moraitou, K.</creatorcontrib><creatorcontrib>Papazahariadou, R.</creatorcontrib><creatorcontrib>Batzios, C.</creatorcontrib><creatorcontrib>Conti, P.</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Animal Behavior Abstracts</collection><collection>Ecology Abstracts</collection><collection>Agricultural Science Collection</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Public Health Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Agricultural & Environmental Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>ASFA: Aquatic Sciences and Fisheries Abstracts</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) 1: Biological Sciences & Living Resources</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) Professional</collection><collection>Agricultural Science Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of helminthology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Theodorides, Y.</au><au>Frydas, S.</au><au>Rallis, T.</au><au>Adamama-Moraitou, K.</au><au>Papazahariadou, R.</au><au>Batzios, C.</au><au>Conti, P.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>MCP-1 and MIP-2 levels during Echinococcus granulosus infections in mice</atitle><jtitle>Journal of helminthology</jtitle><addtitle>J. Helminthol</addtitle><date>2001-06-01</date><risdate>2001</risdate><volume>75</volume><issue>2</issue><spage>205</spage><epage>208</epage><pages>205-208</pages><issn>0022-149X</issn><eissn>1475-2697</eissn><coden>JOHLAT</coden><abstract>Ten BALB/c mice were infected with the cestode Echinococcus granulosus. After the infection, serum was collected at different periods of time and monocyte chemotactic protein-1 (MCP-1) and macrophage inflammatory protein-2 (MIP-2) were determined. The level of MCP-1 increased from 290±12 pg ml-1 (mean±SD) at day 20 post infection (p.i.), to a maximum of 820±23 pg ml-1 on day 60 p.i., then decreased to 460±12.6 pg ml-1 on day 130 p.i. A second peak was observed at day 150 p.i. In addition, MIP-2 was detectable in serum as late as day 100 p.i. The highest level (100±11 pg ml-1) was observed on day 130 p.i., and decreased thereafter. Serum from noninfected animals (controls) contained no detectable levels of either MCP-1 or MIP-2. However, MCP-1 and MIP-2 appear to be implicated in E. granulosus infections, but their exact role during the disease is under determination.</abstract><cop>Cambridge, UK</cop><pub>Cambridge University Press</pub><pmid>11520447</pmid><doi>10.1079/JOH200139</doi><tpages>4</tpages></addata></record> |
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| subjects | Animals Antibodies, Monoclonal Biological and medical sciences Chemokine CCL2 - blood Chemokine CXCL2 Chemokines - blood Disease Progression Echinococcosis, Hepatic - immunology Echinococcosis, Hepatic - veterinary Enzyme-Linked Immunosorbent Assay - methods Experimental helminthic diseases. Models Helminthic diseases Infectious diseases Medical sciences Mice Mice, Inbred BALB C Parasitic diseases Regression Analysis Time Factors |
| title | MCP-1 and MIP-2 levels during Echinococcus granulosus infections in mice |
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