Crow-Fukase Syndrome with Ischemic Cardiomyopathy

A 31-year-old man was admitted to our hospital for further evaluation of heart failure symptoms. Crow-Fukase syndrome was diagnosed on the basis of findings of polyneuropathy, hepatomegaly, monoclonal hypergammaglobulinemia, and hypertrichosis. Dipyridamole-stress thallium-201 perfusion imaging, con...

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Veröffentlicht in:Internal Medicine 2001, Vol.40(8), pp.726-730
Hauptverfasser: ICHIKAWA, Yoshihiko, NAKATA, Tomoaki, OHHATA, Junichi, WAKABAYASHI, Takeru, SASAO, Hisataka, TSUCHIHASHI, Kazufumi, SHIMAMOTO, Kazuaki, CHIBA, Susumu, MATSUMOTO, Hiroyuki
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container_end_page 730
container_issue 8
container_start_page 726
container_title Internal Medicine
container_volume 40
creator ICHIKAWA, Yoshihiko
NAKATA, Tomoaki
OHHATA, Junichi
WAKABAYASHI, Takeru
SASAO, Hisataka
TSUCHIHASHI, Kazufumi
SHIMAMOTO, Kazuaki
CHIBA, Susumu
MATSUMOTO, Hiroyuki
description A 31-year-old man was admitted to our hospital for further evaluation of heart failure symptoms. Crow-Fukase syndrome was diagnosed on the basis of findings of polyneuropathy, hepatomegaly, monoclonal hypergammaglobulinemia, and hypertrichosis. Dipyridamole-stress thallium-201 perfusion imaging, contrast left ventriculography, and coronary angiography revealed a markedly dilated and dysfunctioning left ventricle, extensive reversible ischemia with fixed defect, and multiple coronary lesions. Histopathology of myocardial biopsy specimens demonstrated ischemia-induced myocardial necrosis. These findings suggested that ischemic cardiomyopathy, probably due to inflammatory reactions of coronary arteries in Crow-Fukase syndrome, was responsible for the heart failure symptoms and left ventricular dysfunction in this patient. (Internal Medicine 40: 726-730, 2001)
doi_str_mv 10.2169/internalmedicine.40.726
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Crow-Fukase syndrome was diagnosed on the basis of findings of polyneuropathy, hepatomegaly, monoclonal hypergammaglobulinemia, and hypertrichosis. Dipyridamole-stress thallium-201 perfusion imaging, contrast left ventriculography, and coronary angiography revealed a markedly dilated and dysfunctioning left ventricle, extensive reversible ischemia with fixed defect, and multiple coronary lesions. Histopathology of myocardial biopsy specimens demonstrated ischemia-induced myocardial necrosis. These findings suggested that ischemic cardiomyopathy, probably due to inflammatory reactions of coronary arteries in Crow-Fukase syndrome, was responsible for the heart failure symptoms and left ventricular dysfunction in this patient. 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Nmr spectrometry ; Radionuclide Imaging ; Thallium ; Vasodilator Agents ; Ventricular Dysfunction, Left - diagnosis ; Ventricular Dysfunction, Left - etiology ; Ventricular Dysfunction, Left - physiopathology</subject><ispartof>Internal Medicine, 2001, Vol.40(8), pp.726-730</ispartof><rights>The Japanese Society of Internal Medicine</rights><rights>2002 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c502t-b4daf80aaad4bb6460aa21c7d1144f73adf65992b12ca2e78709dd8038027e743</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,1881,27915,27916</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&amp;idt=14072050$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11518111$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>ICHIKAWA, Yoshihiko</creatorcontrib><creatorcontrib>NAKATA, Tomoaki</creatorcontrib><creatorcontrib>OHHATA, Junichi</creatorcontrib><creatorcontrib>WAKABAYASHI, Takeru</creatorcontrib><creatorcontrib>SASAO, Hisataka</creatorcontrib><creatorcontrib>TSUCHIHASHI, Kazufumi</creatorcontrib><creatorcontrib>SHIMAMOTO, Kazuaki</creatorcontrib><creatorcontrib>CHIBA, Susumu</creatorcontrib><creatorcontrib>MATSUMOTO, Hiroyuki</creatorcontrib><title>Crow-Fukase Syndrome with Ischemic Cardiomyopathy</title><title>Internal Medicine</title><addtitle>Intern. Med.</addtitle><description>A 31-year-old man was admitted to our hospital for further evaluation of heart failure symptoms. Crow-Fukase syndrome was diagnosed on the basis of findings of polyneuropathy, hepatomegaly, monoclonal hypergammaglobulinemia, and hypertrichosis. Dipyridamole-stress thallium-201 perfusion imaging, contrast left ventriculography, and coronary angiography revealed a markedly dilated and dysfunctioning left ventricle, extensive reversible ischemia with fixed defect, and multiple coronary lesions. Histopathology of myocardial biopsy specimens demonstrated ischemia-induced myocardial necrosis. These findings suggested that ischemic cardiomyopathy, probably due to inflammatory reactions of coronary arteries in Crow-Fukase syndrome, was responsible for the heart failure symptoms and left ventricular dysfunction in this patient. (Internal Medicine 40: 726-730, 2001)</description><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>Cardiovascular system</subject><subject>congestive heart failure</subject><subject>Coronary Angiography</subject><subject>coronary artery disease</subject><subject>Dipyridamole</subject><subject>Electrocardiography</subject><subject>Humans</subject><subject>Investigative techniques, diagnostic techniques (general aspects)</subject><subject>Male</subject><subject>Medical sciences</subject><subject>myocardial ischemia</subject><subject>Myocardial Ischemia - complications</subject><subject>Myocardial Ischemia - diagnosis</subject><subject>Myocardial Ischemia - etiology</subject><subject>Myocardial Ischemia - physiopathology</subject><subject>POEMS syndrome</subject><subject>POEMS Syndrome - complications</subject><subject>POEMS Syndrome - diagnosis</subject><subject>POEMS Syndrome - diagnostic imaging</subject><subject>POEMS Syndrome - physiopathology</subject><subject>Radiodiagnosis. Nmr imagery. Nmr spectrometry</subject><subject>Radionuclide Imaging</subject><subject>Thallium</subject><subject>Vasodilator Agents</subject><subject>Ventricular Dysfunction, Left - diagnosis</subject><subject>Ventricular Dysfunction, Left - etiology</subject><subject>Ventricular Dysfunction, Left - physiopathology</subject><issn>0918-2918</issn><issn>1349-7235</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2001</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNplkE1LAzEQhoMotlb_gvait62ZbHazOUrxCwoK6jnMJlkb3Y-a7FL6701pUdDLTCDPJM-8hFwAnTHI5bVre-tbrBtrnHatnXE6Eyw_IGNIuUwES7NDMqYSioTFMiInIXxQmhZCsmMyAsigAIAxgbnv1snd8InBTl82rfFdY6dr1y-nj0EvbeP0dI7euK7ZdCvsl5tTclRhHezZvk_I293t6_whWTzdP85vFonOKOuTkhusCoqIhpdlzvN4ZKCFAeC8EimaKs-kZCUwjcyKQlBpTBEVKRNW8HRCrnbvrnz3NdjQq8YFbesaW9sNQYnoz6UsIih2oPZdCN5WauVdg36jgKptWupvWopTFdOKk-f7L4Yy3v3O7eOJwOUewKCxrjy22oVfjlPBaEYj97zjPkKP7_YHQN87Xdt_AhAX30oUuxJdflC9RK9sm34DByqVAQ</recordid><startdate>20010801</startdate><enddate>20010801</enddate><creator>ICHIKAWA, Yoshihiko</creator><creator>NAKATA, Tomoaki</creator><creator>OHHATA, Junichi</creator><creator>WAKABAYASHI, Takeru</creator><creator>SASAO, Hisataka</creator><creator>TSUCHIHASHI, Kazufumi</creator><creator>SHIMAMOTO, Kazuaki</creator><creator>CHIBA, Susumu</creator><creator>MATSUMOTO, Hiroyuki</creator><general>The Japanese Society of Internal Medicine</general><general>Japanese Society of Internal Medicine</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20010801</creationdate><title>Crow-Fukase Syndrome with Ischemic Cardiomyopathy</title><author>ICHIKAWA, Yoshihiko ; NAKATA, Tomoaki ; OHHATA, Junichi ; WAKABAYASHI, Takeru ; SASAO, Hisataka ; TSUCHIHASHI, Kazufumi ; SHIMAMOTO, Kazuaki ; CHIBA, Susumu ; MATSUMOTO, Hiroyuki</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c502t-b4daf80aaad4bb6460aa21c7d1144f73adf65992b12ca2e78709dd8038027e743</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2001</creationdate><topic>Adult</topic><topic>Biological and medical sciences</topic><topic>Cardiovascular system</topic><topic>congestive heart failure</topic><topic>Coronary Angiography</topic><topic>coronary artery disease</topic><topic>Dipyridamole</topic><topic>Electrocardiography</topic><topic>Humans</topic><topic>Investigative techniques, diagnostic techniques (general aspects)</topic><topic>Male</topic><topic>Medical sciences</topic><topic>myocardial ischemia</topic><topic>Myocardial Ischemia - complications</topic><topic>Myocardial Ischemia - diagnosis</topic><topic>Myocardial Ischemia - etiology</topic><topic>Myocardial Ischemia - physiopathology</topic><topic>POEMS syndrome</topic><topic>POEMS Syndrome - complications</topic><topic>POEMS Syndrome - diagnosis</topic><topic>POEMS Syndrome - diagnostic imaging</topic><topic>POEMS Syndrome - physiopathology</topic><topic>Radiodiagnosis. Nmr imagery. Nmr spectrometry</topic><topic>Radionuclide Imaging</topic><topic>Thallium</topic><topic>Vasodilator Agents</topic><topic>Ventricular Dysfunction, Left - diagnosis</topic><topic>Ventricular Dysfunction, Left - etiology</topic><topic>Ventricular Dysfunction, Left - physiopathology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>ICHIKAWA, Yoshihiko</creatorcontrib><creatorcontrib>NAKATA, Tomoaki</creatorcontrib><creatorcontrib>OHHATA, Junichi</creatorcontrib><creatorcontrib>WAKABAYASHI, Takeru</creatorcontrib><creatorcontrib>SASAO, Hisataka</creatorcontrib><creatorcontrib>TSUCHIHASHI, Kazufumi</creatorcontrib><creatorcontrib>SHIMAMOTO, Kazuaki</creatorcontrib><creatorcontrib>CHIBA, Susumu</creatorcontrib><creatorcontrib>MATSUMOTO, Hiroyuki</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Internal Medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>ICHIKAWA, Yoshihiko</au><au>NAKATA, Tomoaki</au><au>OHHATA, Junichi</au><au>WAKABAYASHI, Takeru</au><au>SASAO, Hisataka</au><au>TSUCHIHASHI, Kazufumi</au><au>SHIMAMOTO, Kazuaki</au><au>CHIBA, Susumu</au><au>MATSUMOTO, Hiroyuki</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Crow-Fukase Syndrome with Ischemic Cardiomyopathy</atitle><jtitle>Internal Medicine</jtitle><addtitle>Intern. 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source J-STAGE Free; MEDLINE; EZB-FREE-00999 freely available EZB journals
subjects Adult
Biological and medical sciences
Cardiovascular system
congestive heart failure
Coronary Angiography
coronary artery disease
Dipyridamole
Electrocardiography
Humans
Investigative techniques, diagnostic techniques (general aspects)
Male
Medical sciences
myocardial ischemia
Myocardial Ischemia - complications
Myocardial Ischemia - diagnosis
Myocardial Ischemia - etiology
Myocardial Ischemia - physiopathology
POEMS syndrome
POEMS Syndrome - complications
POEMS Syndrome - diagnosis
POEMS Syndrome - diagnostic imaging
POEMS Syndrome - physiopathology
Radiodiagnosis. Nmr imagery. Nmr spectrometry
Radionuclide Imaging
Thallium
Vasodilator Agents
Ventricular Dysfunction, Left - diagnosis
Ventricular Dysfunction, Left - etiology
Ventricular Dysfunction, Left - physiopathology
title Crow-Fukase Syndrome with Ischemic Cardiomyopathy
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