Immunoreactive Pit-1 Protein in Hyperplastic Pars Intermedia Induced by Calcitonin of the Rat Pituitary Gland

To elucidate the effects of synthetic salmon calcitonin (sCT) on the cells in the rat pituitary gland, we histopathologically and immunohistochemically examined the early changes after 4 or 13 weeks treatment with sCT 120IU/kg. Focal proliferative lesions of the anterior pituitary glands were consis...

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Veröffentlicht in:	ENDOCRINE JOURNAL 2000, Vol.47(1), pp.13-20
Hauptverfasser:	MURAKOSHI, MASANORI, IKEDA, RIE, HORIUCHI, TOSHI, NAKAYAMA, TAKAHARU, KUROTANI, REIKO, OSAMURA, R. YOSHIYUKI
Format:	Artikel
Sprache:	eng
Schlagworte:	Alpha-subunit Animals Calcitonin Calcitonin - pharmacology DNA-Binding Proteins - metabolism Hyperplasia Immunohistochemistry Male Pit-1 Pituitary gland Pituitary Gland - drug effects Pituitary Gland, Anterior - metabolism Pituitary Gland, Anterior - pathology Rat Rats Rats, Sprague-Dawley Salmon Transcription Factor Pit-1 Transcription Factors - metabolism
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