EGTA treatment of human airways in vitro unmasks M1/MUC5AC mucin in submucosal glands

Mucin staining can be used to evaluate secretory activity of human airways. However, mucin epitopes may be masked by physicochemical properties of the secretions. The aim of this investigation was to examine the effects of the calcium chelator, ethyleneglycol-bis-(beta-aminoethylether)-N,N,N',N...

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Veröffentlicht in:	The European respiratory journal 2001-07, Vol.18 (1), p.176-183
Hauptverfasser:	Roger, P, Gascard, J-P, Bara, J, Dulmet, E, Brink, C
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Bronchi - pathology Egtazic Acid - pharmacology Humans In Vitro Techniques Investigative techniques, diagnostic techniques (general aspects) Lung Neoplasms - pathology Medical sciences Mucin 5AC Mucins - analysis Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Respiratory Mucosa - pathology Respiratory system Sensitivity and Specificity
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