Antigen-Specific Blockade of T Cells In Vivo Using Dimeric MHC Peptide

Ag-specific immune tolerance in clinical organ transplantation is currently an unrealized but critical goal of transplant biology. The specificity and avidity of multimerized MHC-peptide complexes suggests their potential ability to modulate T cell sensitization and effector functions. In this study...

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Veröffentlicht in:	The Journal of immunology (1950) 2001-09, Vol.167 (5), p.2555-2560
Hauptverfasser:	O'Herrin, Sean M, Slansky, Jill E, Tang, Q, Markiewicz, Mary A, Gajewski, Thomas F, Pardoll, Drew M, Schneck, Jonathan P, Bluestone, Jeffrey A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cytotoxicity, Immunologic Dimerization DNA-Binding Proteins - genetics DNA-Binding Proteins - metabolism H-2 Antigens - chemistry H-2 Antigens - metabolism Humans Immune Tolerance In Vitro Techniques Mice Mice, Inbred BALB C Mice, Knockout Mice, Transgenic Nuclear Proteins Protein-Tyrosine Kinases - metabolism Receptors, Antigen, T-Cell - genetics Receptors, Antigen, T-Cell - metabolism Signal Transduction T-Lymphocytes, Cytotoxic - immunology T-Lymphocytes, Cytotoxic - metabolism Transplantation Immunology ZAP-70 Protein-Tyrosine Kinase
Online-Zugang:	Volltext
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