Effects of Circadian Regulation and Rest—Activity State on Spontaneous Seizures in a Rat Model of Limbic Epilepsy

Purpose: Circadian regulation via the suprachiasmatic nuclei and rest–activity state may influence expression of limbic seizures. Methods: Male rats (n = 14) were made epileptic by electrical stimulation of the hippocampus, causing limbic status epilepticus and subsequent seizures. We monitored seiz...

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Veröffentlicht in:	Epilepsia (Copenhagen) 2000-05, Vol.41 (5), p.502-509
Hauptverfasser:	Quigg, Mark, Clayburn, Hope, Straume, Martin, Menaker, Michael, Bertram, Edward H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Body Temperature Regulation - physiology Chronobiology Circadian Rhythm - physiology Circadian rhythms Disease Models, Animal Electric Stimulation Epilepsy Epilepsy - physiopathology Epilepsy, Temporal Lobe - physiopathology Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy Hypothalamus Limbic System - physiopathology Male Medical sciences Mesial temporal lobe epilepsy Motor Activity - physiology Nervous system (semeiology, syndromes) Neurology Rats Rats, Sprague-Dawley Suprachiasmatic Nucleus - physiology Thermoregulation
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