Calcitonin-gene related peptide (CGRP) inhibits interleukin-7-induced pre-B cell colony formation

Calcitonin gene‐related peptide (CGRP) is a sensory neuropeptide with inflammatory and immunoregulatory activities. Its role in B lymphocyte development was investigated using a pre‐B cell colony‐forming assay. Physiological concentrations of CGRP inhibited pre‐B cell responses to interleukin‐7 (IL‐...

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Veröffentlicht in:	Journal of leukocyte biology 2000-05, Vol.67 (5), p.669-676
Hauptverfasser:	Fernandez, Stefan, Knopf, Melissa A., McGillis, Joseph P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenomedullin Animals B lymphocytes B-Lymphocytes - cytology B-Lymphocytes - drug effects B-Lymphocytes - immunology bone marrow Bone Marrow Cells - cytology Bone Marrow Cells - physiology calcitonin Calcitonin - pharmacology calcitonin gene-related peptide Calcitonin Gene-Related Peptide - pharmacology Cell Adhesion Cells, Cultured Colony-Forming Units Assay Female growth factors hematopoiesis Hematopoietic Stem Cells - cytology Hematopoietic Stem Cells - drug effects Interleukin-7 - antagonists & inhibitors Interleukin-7 - pharmacology Macrophages - drug effects Macrophages - immunology Male Mice Mice, Inbred BALB C neuroimmunology Peptide Fragments - pharmacology Peptides - pharmacology substance P Substance P - pharmacology
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