Similar myeloid recovery despite superior overall engraftment in NOD/SCID mice after transplantation of human CD34+ cells from umbilical cord blood as compared to adult sources

Umbilical cord blood (UCB), bone marrow (BM) and mobilized peripheral blood (mPB) are used as sources of hematopoietic stem cells for transplantation. The NOD/SCID mouse model was used to compare the lineage-specific repopulating potential of CD34(+) cells derived from these sources. Six to 8 weeks...

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Veröffentlicht in:	Bone marrow transplantation (Basingstoke) 2001-07, Vol.28 (2), p.163-171
Hauptverfasser:	NOORT, W. A, WILPSHAAR, J, HERTOGH, C. D. P, RAD, M, LURVINK, E. G. A, VAN LUXEMBURG-HEIJS, S. A. P, ZWINDERMAN, K, VERWEY, R. A, WILLEMZE, R, FALKENBURG, J. H. F
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Animals Antibodies Antigens, CD - blood Antigens, CD34 - blood Biological and medical sciences Blood Bone marrow Bone Marrow Cells - cytology Bone Marrow Cells - immunology Bone marrow transplantation Bone marrow, stem cells transplantation. Graft versus host reaction CD34 antigen CD45 antigen Cord blood Engraftment Fetal Blood - cytology Flow Cytometry Hematopoietic Stem Cell Transplantation Hematopoietic stem cells Humans Infant, Newborn Liver - cytology Liver - immunology Medical sciences Mice Mice, Inbred NOD Mice, SCID Myeloid cells Peripheral blood Recovery Spleen Spleen - cytology Spleen - immunology Stem cell transplantation Stem cells Thymus Gland - cytology Thymus Gland - immunology Transfusions. Complications. Transfusion reactions. Cell and gene therapy Transplantation Transplantation, Heterologous - physiology Transplants Transplants & implants Umbilical cord
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