Novel Amidohydrolytic Reactions in Oxidative Pyrimidine Metabolism: Analysis of the Barbiturase Reaction and Discovery of a Novel Enzyme, Ureidomalonase

Amidohydrolytic reactions in oxidative pyrimidine metabolism were investigated in detail. Barbiturase has been reported to catalyze the amidohydrolysis of barbituric acid to urea and malonic acid. However, purification of the enzyme revealed that it catalyzes the ring-opening of barbituric acid to u...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Biochemical and biophysical research communications 2001-08, Vol.286 (1), p.222-226
Hauptverfasser:	Soong, Chee-Leong, Ogawa, Jun, Shimizu, Sakayu
Format:	Artikel
Sprache:	eng
Schlagworte:	Amides - metabolism Amidohydrolases - biosynthesis Amidohydrolases - metabolism amidohydrolysis barbiturase barbituric acid Enzyme Induction Hydrolysis Oxidation-Reduction oxidative pyrimidine metabolism Pyrimidines - metabolism Rhodococcus - enzymology Rhodococcus - metabolism ureidomalonase ureidomalonic acid
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!