Electrophoresis in Nanometer Inner Diameter Capillaries with Electrochemical Detection
Separations have been achieved in 770- and 430-nm-inner diameter capillaries. The extremely low sample volumes involved in the study of biological microenvironments such as single cells has led to the desire to develop separation techniques in these ultrasmall capillaries. Total sample volumes as lo...
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| Veröffentlicht in: | Analytical chemistry (Washington) 2001-08, Vol.73 (15), p.3687-3690 |
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| container_title | Analytical chemistry (Washington) |
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| creator | Woods, Lori A Roddy, Thomas P Paxon, Tracy L Ewing, Andrew G |
| description | Separations have been achieved in 770- and 430-nm-inner diameter capillaries. The extremely low sample volumes involved in the study of biological microenvironments such as single cells has led to the desire to develop separation techniques in these ultrasmall capillaries. Total sample volumes as low as 12 fL have been injected using these nanometer inner diameter capillaries. Separations of several catecholamines have been accomplished in these submicrometer capillaries using both capillary zone electrophoresis and micellar electrokinetic chromatography with end-column amperometric detection. |
| doi_str_mv | 10.1021/ac010053e |
| format | Article |
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The extremely low sample volumes involved in the study of biological microenvironments such as single cells has led to the desire to develop separation techniques in these ultrasmall capillaries. Total sample volumes as low as 12 fL have been injected using these nanometer inner diameter capillaries. Separations of several catecholamines have been accomplished in these submicrometer capillaries using both capillary zone electrophoresis and micellar electrokinetic chromatography with end-column amperometric detection.</description><identifier>ISSN: 0003-2700</identifier><identifier>EISSN: 1520-6882</identifier><identifier>DOI: 10.1021/ac010053e</identifier><identifier>PMID: 11510835</identifier><identifier>CODEN: ANCHAM</identifier><language>eng</language><publisher>Washington, DC: American Chemical Society</publisher><subject>Analytical chemistry ; Catecholamines - analysis ; Cells ; Chemistry ; Chromatographic methods and physical methods associated with chromatography ; Chromatography ; Chromatography, Micellar Electrokinetic Capillary ; Electrochemistry ; Electrophoresis, Capillary - methods ; Exact sciences and technology ; Other chromatographic methods</subject><ispartof>Analytical chemistry (Washington), 2001-08, Vol.73 (15), p.3687-3690</ispartof><rights>Copyright © 2001 American Chemical Society</rights><rights>2001 INIST-CNRS</rights><rights>Copyright American Chemical Society Aug 1, 2001</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a405t-6d8ad78b44a76cdbdbc8b46847e2cce64999e246217db28b6d14945144f6a88a3</citedby><cites>FETCH-LOGICAL-a405t-6d8ad78b44a76cdbdbc8b46847e2cce64999e246217db28b6d14945144f6a88a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://pubs.acs.org/doi/pdf/10.1021/ac010053e$$EPDF$$P50$$Gacs$$H</linktopdf><linktohtml>$$Uhttps://pubs.acs.org/doi/10.1021/ac010053e$$EHTML$$P50$$Gacs$$H</linktohtml><link.rule.ids>314,777,781,2752,27057,27905,27906,56719,56769</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=1093561$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11510835$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Woods, Lori A</creatorcontrib><creatorcontrib>Roddy, Thomas P</creatorcontrib><creatorcontrib>Paxon, Tracy L</creatorcontrib><creatorcontrib>Ewing, Andrew G</creatorcontrib><title>Electrophoresis in Nanometer Inner Diameter Capillaries with Electrochemical Detection</title><title>Analytical chemistry (Washington)</title><addtitle>Anal. 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Separations of several catecholamines have been accomplished in these submicrometer capillaries using both capillary zone electrophoresis and micellar electrokinetic chromatography with end-column amperometric detection.</description><subject>Analytical chemistry</subject><subject>Catecholamines - analysis</subject><subject>Cells</subject><subject>Chemistry</subject><subject>Chromatographic methods and physical methods associated with chromatography</subject><subject>Chromatography</subject><subject>Chromatography, Micellar Electrokinetic Capillary</subject><subject>Electrochemistry</subject><subject>Electrophoresis, Capillary - methods</subject><subject>Exact sciences and technology</subject><subject>Other chromatographic methods</subject><issn>0003-2700</issn><issn>1520-6882</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2001</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpl0E1v1DAQBmALgehSOPAHUIQAiUNgJnFs54i2LVtU8SEKV2vizGpd8rG1s6L8e4wStQgutiw_fjV-hXiK8AahwLfkAAGqku-JFVYF5MqY4r5YAUCZFxrgSDyK8QoAEVA9FEeIFYIpq5X4ftqxm8K4342Bo4-ZH7KPNIw9Txyy82FI64mn-bimve86Cp5j9tNPu2x57Hbce0dddpKYm_w4PBYPttRFfrLsx-Lb2enlepNffHp_vn53kZOEaspVa6jVppGStHJt0zYuHZSRmgvnWMm6rrmQqkDdNoVpVIuylhVKuVVkDJXH4tWcuw_j9YHjZHsfHachBx4P0WqE2gDqBJ__A6_GQxjSbDaFG2NSIQm9npELY4yBt3YffE_hl0Wwf5q2t00n-2wJPDQ9t3dyqTaBFwugmLrZBhqcj38l1mWlMLF8Zj5OfHN7TeGHVbrUlb38_NWaD5vyiyyl3ST_cvbk4t0f_p_vNxEAn5w</recordid><startdate>20010801</startdate><enddate>20010801</enddate><creator>Woods, Lori A</creator><creator>Roddy, Thomas P</creator><creator>Paxon, Tracy L</creator><creator>Ewing, Andrew G</creator><general>American Chemical Society</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QF</scope><scope>7QO</scope><scope>7QQ</scope><scope>7SC</scope><scope>7SE</scope><scope>7SP</scope><scope>7SR</scope><scope>7TA</scope><scope>7TB</scope><scope>7TM</scope><scope>7U5</scope><scope>7U7</scope><scope>7U9</scope><scope>8BQ</scope><scope>8FD</scope><scope>C1K</scope><scope>F28</scope><scope>FR3</scope><scope>H8D</scope><scope>H8G</scope><scope>H94</scope><scope>JG9</scope><scope>JQ2</scope><scope>KR7</scope><scope>L7M</scope><scope>L~C</scope><scope>L~D</scope><scope>P64</scope><scope>7X8</scope></search><sort><creationdate>20010801</creationdate><title>Electrophoresis in Nanometer Inner Diameter Capillaries with Electrochemical Detection</title><author>Woods, Lori A ; 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Chem</addtitle><date>2001-08-01</date><risdate>2001</risdate><volume>73</volume><issue>15</issue><spage>3687</spage><epage>3690</epage><pages>3687-3690</pages><issn>0003-2700</issn><eissn>1520-6882</eissn><coden>ANCHAM</coden><abstract>Separations have been achieved in 770- and 430-nm-inner diameter capillaries. The extremely low sample volumes involved in the study of biological microenvironments such as single cells has led to the desire to develop separation techniques in these ultrasmall capillaries. Total sample volumes as low as 12 fL have been injected using these nanometer inner diameter capillaries. Separations of several catecholamines have been accomplished in these submicrometer capillaries using both capillary zone electrophoresis and micellar electrokinetic chromatography with end-column amperometric detection.</abstract><cop>Washington, DC</cop><pub>American Chemical Society</pub><pmid>11510835</pmid><doi>10.1021/ac010053e</doi><tpages>4</tpages></addata></record> |
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| ispartof | Analytical chemistry (Washington), 2001-08, Vol.73 (15), p.3687-3690 |
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| language | eng |
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| source | MEDLINE; ACS Publications |
| subjects | Analytical chemistry Catecholamines - analysis Cells Chemistry Chromatographic methods and physical methods associated with chromatography Chromatography Chromatography, Micellar Electrokinetic Capillary Electrochemistry Electrophoresis, Capillary - methods Exact sciences and technology Other chromatographic methods |
| title | Electrophoresis in Nanometer Inner Diameter Capillaries with Electrochemical Detection |
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