An outcome study of breast reconstruction: presurgical identification of risk factors for complications
Breast reconstruction following mastectomy has been shown to have a salutary effect on the overall psychological well-being of women being treated for breast cancer. Unfortunately, however, not every patient is an ideal candidate for reconstruction. Complications stemming from reconstructive surgery...
Gespeichert in:
| Veröffentlicht in: | Annals of surgical oncology 2001-08, Vol.8 (7), p.586-591 |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 591 |
|---|---|
| container_issue | 7 |
| container_start_page | 586 |
| container_title | Annals of surgical oncology |
| container_volume | 8 |
| creator | Lin, K Y Johns, F R Gibson, J Long, M Drake, D B Moore, M M |
| description | Breast reconstruction following mastectomy has been shown to have a salutary effect on the overall psychological well-being of women being treated for breast cancer. Unfortunately, however, not every patient is an ideal candidate for reconstruction. Complications stemming from reconstructive surgery can cause significant morbidity, the most important of which may be the delay of subsequent adjuvant antineoplastic therapies, and therefore may not be in the best interests of the patient.
A retrospective study was performed on a consecutive series of 123 breast reconstructions in 98 patients, performed by one of two plastic surgeons, in a university setting over a 5-year period, for all surgical outcomes. Specifically, wound-healing complications, infections, and reoperations leading to the potential delay of subsequent chemotherapy or radiotherapy were recorded, and possible risk factors leading to these were sought.
Three presurgical risk factors were found to have a statistically significant influence on the development of complications following breast reconstruction. These were: (1) increasing obesity, defined by the body mass index, (2) an active or recent ( |
| doi_str_mv | 10.1007/s10434-001-0586-3 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_71097345</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>931568311</sourcerecordid><originalsourceid>FETCH-LOGICAL-c256t-e7bd2f55cd86e5e15abd750f5962de2f3f7212dbde940c06a699b8da2b3036ce3</originalsourceid><addsrcrecordid>eNpdkU1LxDAQhoMofv8ALxI8eKtOkiZtvcniFwhe9BzSZLJUu82apAf_vVl2QfA0w8zzvgzzEnLB4IYBNLeJQS3qCoBVIFtViT1yzGSZ1Kpl-6UH1VYdV_KInKT0WbhGgDwkR4xJaBWHY7K8n2iYsw0rpCnP7ocGT_uIJmUa0YYp5TjbPITpjq4jpjkuB2tGOjic8uBLv9ltRHFIX9Qbm0NM1IdIi-d63AHpjBx4MyY839VT8vH48L54rl7fnl4W96-V5VLlCpvecS-lda1CiUya3jUSvOwUd8i98A1n3PUOuxosKKO6rm-d4b0AoSyKU3K99V3H8D1jyno1JIvjaCYMc9INg64RtSzg1T_wM8xxKrdpzhshlWJ1gdgWsjGkFNHrdRxWJv5oBnoTgd5GoMtr9SYCLYrmcmc89yt0f4rdz8UveOeDnQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>227356614</pqid></control><display><type>article</type><title>An outcome study of breast reconstruction: presurgical identification of risk factors for complications</title><source>MEDLINE</source><source>SpringerNature Journals</source><creator>Lin, K Y ; Johns, F R ; Gibson, J ; Long, M ; Drake, D B ; Moore, M M</creator><creatorcontrib>Lin, K Y ; Johns, F R ; Gibson, J ; Long, M ; Drake, D B ; Moore, M M</creatorcontrib><description>Breast reconstruction following mastectomy has been shown to have a salutary effect on the overall psychological well-being of women being treated for breast cancer. Unfortunately, however, not every patient is an ideal candidate for reconstruction. Complications stemming from reconstructive surgery can cause significant morbidity, the most important of which may be the delay of subsequent adjuvant antineoplastic therapies, and therefore may not be in the best interests of the patient.
A retrospective study was performed on a consecutive series of 123 breast reconstructions in 98 patients, performed by one of two plastic surgeons, in a university setting over a 5-year period, for all surgical outcomes. Specifically, wound-healing complications, infections, and reoperations leading to the potential delay of subsequent chemotherapy or radiotherapy were recorded, and possible risk factors leading to these were sought.
Three presurgical risk factors were found to have a statistically significant influence on the development of complications following breast reconstruction. These were: (1) increasing obesity, defined by the body mass index, (2) an active or recent (<5 year) history of cigarette smoking, and (3) a history of previous radiation exposure. Odds ratios were used to describe the magnitude of the effect of each factor for the development of complications. An ordinal regression analysis was used to create a nomogram based on this information that can be used to calculate any individual patient's presurgical risk for developing major complications following breast reconstruction, based on the presence of these factors.
It is possible, based on the presence of specific presurgical risk factors, to predict the probability of developing major complications following breast reconstruction. This information can be useful to the referring physician and plastic surgeon alike in determining which patients are the best candidates for breast reconstruction and which type of reconstruction would be best suited for each individual patient.</description><identifier>ISSN: 1068-9265</identifier><identifier>EISSN: 1534-4681</identifier><identifier>DOI: 10.1007/s10434-001-0586-3</identifier><identifier>PMID: 11508620</identifier><language>eng</language><publisher>United States: Springer Nature B.V</publisher><subject>Adult ; Aged ; Body Mass Index ; Breast Neoplasms - radiotherapy ; Breast Neoplasms - surgery ; Contraindications ; Female ; Humans ; Mammaplasty - methods ; Middle Aged ; Necrosis ; Obesity - complications ; Regression Analysis ; Retrospective Studies ; Risk Factors ; Smoking - adverse effects ; Surgical Flaps ; Time Factors ; Tissue Expansion Devices ; Treatment Outcome</subject><ispartof>Annals of surgical oncology, 2001-08, Vol.8 (7), p.586-591</ispartof><rights>The Society of Surgical Oncology, Inc. 2001</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c256t-e7bd2f55cd86e5e15abd750f5962de2f3f7212dbde940c06a699b8da2b3036ce3</citedby><cites>FETCH-LOGICAL-c256t-e7bd2f55cd86e5e15abd750f5962de2f3f7212dbde940c06a699b8da2b3036ce3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11508620$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lin, K Y</creatorcontrib><creatorcontrib>Johns, F R</creatorcontrib><creatorcontrib>Gibson, J</creatorcontrib><creatorcontrib>Long, M</creatorcontrib><creatorcontrib>Drake, D B</creatorcontrib><creatorcontrib>Moore, M M</creatorcontrib><title>An outcome study of breast reconstruction: presurgical identification of risk factors for complications</title><title>Annals of surgical oncology</title><addtitle>Ann Surg Oncol</addtitle><description>Breast reconstruction following mastectomy has been shown to have a salutary effect on the overall psychological well-being of women being treated for breast cancer. Unfortunately, however, not every patient is an ideal candidate for reconstruction. Complications stemming from reconstructive surgery can cause significant morbidity, the most important of which may be the delay of subsequent adjuvant antineoplastic therapies, and therefore may not be in the best interests of the patient.
A retrospective study was performed on a consecutive series of 123 breast reconstructions in 98 patients, performed by one of two plastic surgeons, in a university setting over a 5-year period, for all surgical outcomes. Specifically, wound-healing complications, infections, and reoperations leading to the potential delay of subsequent chemotherapy or radiotherapy were recorded, and possible risk factors leading to these were sought.
Three presurgical risk factors were found to have a statistically significant influence on the development of complications following breast reconstruction. These were: (1) increasing obesity, defined by the body mass index, (2) an active or recent (<5 year) history of cigarette smoking, and (3) a history of previous radiation exposure. Odds ratios were used to describe the magnitude of the effect of each factor for the development of complications. An ordinal regression analysis was used to create a nomogram based on this information that can be used to calculate any individual patient's presurgical risk for developing major complications following breast reconstruction, based on the presence of these factors.
It is possible, based on the presence of specific presurgical risk factors, to predict the probability of developing major complications following breast reconstruction. This information can be useful to the referring physician and plastic surgeon alike in determining which patients are the best candidates for breast reconstruction and which type of reconstruction would be best suited for each individual patient.</description><subject>Adult</subject><subject>Aged</subject><subject>Body Mass Index</subject><subject>Breast Neoplasms - radiotherapy</subject><subject>Breast Neoplasms - surgery</subject><subject>Contraindications</subject><subject>Female</subject><subject>Humans</subject><subject>Mammaplasty - methods</subject><subject>Middle Aged</subject><subject>Necrosis</subject><subject>Obesity - complications</subject><subject>Regression Analysis</subject><subject>Retrospective Studies</subject><subject>Risk Factors</subject><subject>Smoking - adverse effects</subject><subject>Surgical Flaps</subject><subject>Time Factors</subject><subject>Tissue Expansion Devices</subject><subject>Treatment Outcome</subject><issn>1068-9265</issn><issn>1534-4681</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2001</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNpdkU1LxDAQhoMofv8ALxI8eKtOkiZtvcniFwhe9BzSZLJUu82apAf_vVl2QfA0w8zzvgzzEnLB4IYBNLeJQS3qCoBVIFtViT1yzGSZ1Kpl-6UH1VYdV_KInKT0WbhGgDwkR4xJaBWHY7K8n2iYsw0rpCnP7ocGT_uIJmUa0YYp5TjbPITpjq4jpjkuB2tGOjic8uBLv9ltRHFIX9Qbm0NM1IdIi-d63AHpjBx4MyY839VT8vH48L54rl7fnl4W96-V5VLlCpvecS-lda1CiUya3jUSvOwUd8i98A1n3PUOuxosKKO6rm-d4b0AoSyKU3K99V3H8D1jyno1JIvjaCYMc9INg64RtSzg1T_wM8xxKrdpzhshlWJ1gdgWsjGkFNHrdRxWJv5oBnoTgd5GoMtr9SYCLYrmcmc89yt0f4rdz8UveOeDnQ</recordid><startdate>200108</startdate><enddate>200108</enddate><creator>Lin, K Y</creator><creator>Johns, F R</creator><creator>Gibson, J</creator><creator>Long, M</creator><creator>Drake, D B</creator><creator>Moore, M M</creator><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7TO</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>H94</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>7X8</scope></search><sort><creationdate>200108</creationdate><title>An outcome study of breast reconstruction: presurgical identification of risk factors for complications</title><author>Lin, K Y ; Johns, F R ; Gibson, J ; Long, M ; Drake, D B ; Moore, M M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c256t-e7bd2f55cd86e5e15abd750f5962de2f3f7212dbde940c06a699b8da2b3036ce3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2001</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Body Mass Index</topic><topic>Breast Neoplasms - radiotherapy</topic><topic>Breast Neoplasms - surgery</topic><topic>Contraindications</topic><topic>Female</topic><topic>Humans</topic><topic>Mammaplasty - methods</topic><topic>Middle Aged</topic><topic>Necrosis</topic><topic>Obesity - complications</topic><topic>Regression Analysis</topic><topic>Retrospective Studies</topic><topic>Risk Factors</topic><topic>Smoking - adverse effects</topic><topic>Surgical Flaps</topic><topic>Time Factors</topic><topic>Tissue Expansion Devices</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lin, K Y</creatorcontrib><creatorcontrib>Johns, F R</creatorcontrib><creatorcontrib>Gibson, J</creatorcontrib><creatorcontrib>Long, M</creatorcontrib><creatorcontrib>Drake, D B</creatorcontrib><creatorcontrib>Moore, M M</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Oncogenes and Growth Factors Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>MEDLINE - Academic</collection><jtitle>Annals of surgical oncology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lin, K Y</au><au>Johns, F R</au><au>Gibson, J</au><au>Long, M</au><au>Drake, D B</au><au>Moore, M M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>An outcome study of breast reconstruction: presurgical identification of risk factors for complications</atitle><jtitle>Annals of surgical oncology</jtitle><addtitle>Ann Surg Oncol</addtitle><date>2001-08</date><risdate>2001</risdate><volume>8</volume><issue>7</issue><spage>586</spage><epage>591</epage><pages>586-591</pages><issn>1068-9265</issn><eissn>1534-4681</eissn><abstract>Breast reconstruction following mastectomy has been shown to have a salutary effect on the overall psychological well-being of women being treated for breast cancer. Unfortunately, however, not every patient is an ideal candidate for reconstruction. Complications stemming from reconstructive surgery can cause significant morbidity, the most important of which may be the delay of subsequent adjuvant antineoplastic therapies, and therefore may not be in the best interests of the patient.
A retrospective study was performed on a consecutive series of 123 breast reconstructions in 98 patients, performed by one of two plastic surgeons, in a university setting over a 5-year period, for all surgical outcomes. Specifically, wound-healing complications, infections, and reoperations leading to the potential delay of subsequent chemotherapy or radiotherapy were recorded, and possible risk factors leading to these were sought.
Three presurgical risk factors were found to have a statistically significant influence on the development of complications following breast reconstruction. These were: (1) increasing obesity, defined by the body mass index, (2) an active or recent (<5 year) history of cigarette smoking, and (3) a history of previous radiation exposure. Odds ratios were used to describe the magnitude of the effect of each factor for the development of complications. An ordinal regression analysis was used to create a nomogram based on this information that can be used to calculate any individual patient's presurgical risk for developing major complications following breast reconstruction, based on the presence of these factors.
It is possible, based on the presence of specific presurgical risk factors, to predict the probability of developing major complications following breast reconstruction. This information can be useful to the referring physician and plastic surgeon alike in determining which patients are the best candidates for breast reconstruction and which type of reconstruction would be best suited for each individual patient.</abstract><cop>United States</cop><pub>Springer Nature B.V</pub><pmid>11508620</pmid><doi>10.1007/s10434-001-0586-3</doi><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1068-9265 |
| ispartof | Annals of surgical oncology, 2001-08, Vol.8 (7), p.586-591 |
| issn | 1068-9265 1534-4681 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_71097345 |
| source | MEDLINE; SpringerNature Journals |
| subjects | Adult Aged Body Mass Index Breast Neoplasms - radiotherapy Breast Neoplasms - surgery Contraindications Female Humans Mammaplasty - methods Middle Aged Necrosis Obesity - complications Regression Analysis Retrospective Studies Risk Factors Smoking - adverse effects Surgical Flaps Time Factors Tissue Expansion Devices Treatment Outcome |
| title | An outcome study of breast reconstruction: presurgical identification of risk factors for complications |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-19T07%3A29%3A11IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=An%20outcome%20study%20of%20breast%20reconstruction:%20presurgical%20identification%20of%20risk%20factors%20for%20complications&rft.jtitle=Annals%20of%20surgical%20oncology&rft.au=Lin,%20K%20Y&rft.date=2001-08&rft.volume=8&rft.issue=7&rft.spage=586&rft.epage=591&rft.pages=586-591&rft.issn=1068-9265&rft.eissn=1534-4681&rft_id=info:doi/10.1007/s10434-001-0586-3&rft_dat=%3Cproquest_cross%3E931568311%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=227356614&rft_id=info:pmid/11508620&rfr_iscdi=true |