ERK 1,2 and p38 pathways are involved in the proliferative stimuli mediated by urokinase in osteoblastic SaOS-2 cell line

Bone metastases from prostate origin generate an osteoblastic reaction that is expressed in vitro by increased osteoblast proliferation. The urokinase‐like plasminogen activator (u‐PA) present in the media conditioned by tumoral prostatic cells acting as a ligand of the cellular membrane receptor (u...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of cellular biochemistry 2001-10, Vol.83 (1), p.92-98
Hauptverfasser:	Juretic, Nevenka, Santibáñez, Juan Francisco, Hurtado, Claudia, Martínez, Jorge
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Division - drug effects Electrophoresis, Polyacrylamide Gel Extracellular Matrix - drug effects Extracellular Matrix - metabolism Flavonoids - pharmacology Humans Imidazoles - pharmacology Immunoblotting Kinetics MAP kinase MAP Kinase Signaling System - drug effects metastases Mitogen-Activated Protein Kinase 1 - antagonists & inhibitors Mitogen-Activated Protein Kinase 1 - metabolism Mitogen-Activated Protein Kinase 3 Mitogen-Activated Protein Kinases - antagonists & inhibitors Mitogen-Activated Protein Kinases - metabolism osteoblasts Osteoblasts - cytology Osteoblasts - drug effects Osteoblasts - enzymology Osteoblasts - metabolism p38 Mitogen-Activated Protein Kinases Phosphorylation - drug effects Pyridines - pharmacology Receptors, Cell Surface - metabolism Receptors, Urokinase Plasminogen Activator Tumor Cells, Cultured urokinase Urokinase-Type Plasminogen Activator - metabolism Urokinase-Type Plasminogen Activator - pharmacology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!