Increased acid-sensing ion channel ASIC-3 in inflamed human intestine

Acid-sensing ion channels (ASICs) are expressed by rat sensory neurons and may mediate pain associated with tissue acidosis after inflammation or injury. Our aim was to examine the molecular forms and localization of ASICs in human intestine and dorsal root ganglia using immunochemical techniques, a...

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Veröffentlicht in:	European journal of gastroenterology & hepatology 2001-08, Vol.13 (8), p.891-896
Hauptverfasser:	YIANGOS YIANGOU, FACER, Paul, SMITH, Jacqueline A. M, SANGAMESWARAN, Lakshmi, EGLEN, Richard, BIRCH, Rolfe, KNOWLES, Charles, WILLIAMS, Norman, ANAND, Praveen
Format:	Artikel
Sprache:	eng
Schlagworte:	Acid Sensing Ion Channels Adolescent Adult Aged Biological and medical sciences Blotting, Western Crohn Disease - metabolism Crohn Disease - pathology Digestive system Female Ganglia, Spinal - chemistry Ganglia, Spinal - injuries Humans Immunohistochemistry Inflammation Intestines - chemistry Intestines - innervation Intestines - pathology Investigative techniques, diagnostic techniques (general aspects) Male Medical sciences Membrane Proteins Middle Aged Myenteric Plexus - chemistry Nerve Tissue Proteins Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Sodium Channels - analysis Submucous Plexus - chemistry
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