N-Bromoacetylethanolamine Phosphate as a Probe for the Identification of a Liver Microsomal Glucose-6-Phosphate Transporter Peptide in Rats and Ehrlich Ascites Tumor-Bearing Mice

Hepatic microsomal glucose-6-phosphatase is a multicomponent system composed of substrate/product translocases and a catalytic subunit. Previously we (Foster et al. (1996) Biochim. Biophys. Acta 12, 244–254) demonstrated that N-bromoacetylethanolamine phosphate (BAEP) is a time-dependent, irreversib...

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Veröffentlicht in:	Archives of biochemistry and biophysics 2000-05, Vol.377 (1), p.115-121
Hauptverfasser:	Foster, James D., Stevens, Andrew L., Nordlie, Robert C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Affinity Labels - metabolism Affinity Labels - pharmacology Animals Antiporters - antagonists & inhibitors Antiporters - metabolism Biological Transport - drug effects Carcinoma, Ehrlich Tumor - metabolism Diphosphates - metabolism Ehrlich ascites tumor-bearing mice Ethanolamines - metabolism Ethanolamines - pharmacology glucose-6-phosphatase Glucose-6-Phosphatase - antagonists & inhibitors Glucose-6-Phosphatase - metabolism Glucose-6-Phosphate - metabolism glucose-6-phosphate transporter Hydrolysis - drug effects liver microsomes Male Mice Microsomes, Liver - chemistry Microsomes, Liver - drug effects Microsomes, Liver - metabolism Molecular Weight Monosaccharide Transport Proteins - antagonists & inhibitors Monosaccharide Transport Proteins - metabolism N-bromoacetylethanolamine phosphate Peptides - chemistry Peptides - metabolism Permeability - drug effects Rats Time Factors tosyl-lysine chloromethyl ketone Tosyllysine Chloromethyl Ketone - pharmacology
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