Effects of Tetrandrine on Growth Factor-induced DNA Synthesis and Proliferative Response of Rat Pulmonary Artery Smooth Muscle Cells

The objective of the present study was to investigate the effect of tetrandrine (a plant alkaloid isolated from Stephenia tetrandra) on growth factor-induced DNA synthesis and proliferative responses of rat pulmonary artery smooth muscle cells. Male rat and bovine pulmonary artery smooth muscle cell...

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Veröffentlicht in:	Pulmonary pharmacology & therapeutics 2000-01, Vol.13 (2), p.53-60
Hauptverfasser:	Wang, H.L., Kilfeather, S.A., Martin, G.R., Page, C.P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkaloids - pharmacology Animals Antihypertensive Agents - pharmacology Benzylisoquinolines Cattle Cell Division - drug effects Cell Survival - drug effects DNA - biosynthesis DNA - drug effects Growth Substances - metabolism In Vitro Techniques Male Muscle, Smooth, Vascular - cytology Muscle, Smooth, Vascular - drug effects Nitrendipine - pharmacology Pulmonary Artery - cytology Pulmonary Artery - drug effects Rabbits Rats Rats, Wistar Tetrandrine, Pulmonary arterial smooth muscle cells, Proliferation, Pulmonary Hypertension
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