Alcohol up-regulates udp-glucuronosyltransferase mrna expression in rat liver and in primary rat hepatocyte culture

The interactions between alcohol and cytochrome P-450 enzymes have been well investigated. However, the data regarding the effect of alcohol on the regulation of UDP-glucuronosyltranferase (UGT) activity are less clear. The aim of the present study was to determine the role of alcohol in the regulat...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Life sciences (1973) 2000-01, Vol.66 (7), p.575-584
Hauptverfasser:	Li, Yan Q., Prentice, David A., Howard, Monique L., Mashford, Maurice L., Wilson, Jeremy S., Desmond, Paul V.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cells, Cultured ethanol Ethanol - pharmacology Gene Expression Regulation, Enzymologic - drug effects Glucuronosyltransferase - genetics Isoenzymes - genetics isopentanol liver Liver - cytology Liver - enzymology Male Pentanols - pharmacology Rats Rats, Sprague-Dawley RNA, Messenger - analysis Up-Regulation UPD-glucuronosyltransferase
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!