Lower Concentration of Thalamic N-Acetylaspartate in Patients With Schizophrenia: A Replication Study

OBJECTIVE: Using proton magnetic resonance spectroscopic imaging, the authors measured thalamic N-acetylaspartate (NAA) concentrations in patients with schizophrenia. METHOD: The study included 15 schizophrenic patients on a stable medication regimen and 15 age-matched healthy comparison subjects. C...

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Veröffentlicht in:	The American journal of psychiatry 2001-08, Vol.158 (8), p.1314-1316
Hauptverfasser:	Ende, Gabriele, Braus, Dieter F., Walter, Sigrid, Henn, Fritz A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Adult and adolescent clinical studies Aspartic Acid - analogs & derivatives Aspartic Acid - analysis Biochemistry Biological and medical sciences Choline - analysis Female Functional Laterality Humans Magnetic Resonance Imaging - statistics & numerical data Magnetic Resonance Spectroscopy - statistics & numerical data Male Medical sciences Mental disorders NMR Nuclear magnetic resonance Patients Phosphocreatine - analysis Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Psychoses Schizophrenia Schizophrenia - diagnosis Schizophrenia - metabolism Schizophrenia - physiopathology Thalamus - chemistry Thalamus - physiopathology
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