Physiological basis for use of insulin-like growth factors in reproductive applications: a review

Physiological basis for use of insulin-like growth factors in reproductive applications: a review

The insulin-like growth factors (IGF-I and -II) are ubiquitously expressed factors that regulate cell growth, differentiation and maintenance of differentiated cell function. All aspects of male and female reproduction are influenced by the IGF system. This review will examine the IGF system as it p...

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Veröffentlicht in:Theriogenology 2000-03, Vol.53 (5), p.1147-1156
Hauptverfasser: Lackey, B.R., Gray, S.L.L., Henricks, D.M.
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Female
growth hormone (GH)
insulin-like growth factors (IGF)
Male
reproduction
Reproduction - physiology
Somatomedins - physiology
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Zusammenfassung:The insulin-like growth factors (IGF-I and -II) are ubiquitously expressed factors that regulate cell growth, differentiation and maintenance of differentiated cell function. All aspects of male and female reproduction are influenced by the IGF system. This review will examine the IGF system as it pertains to reproductive physiology and applications.
ISSN:0093-691X
1879-3231
DOI:10.1016/S0093-691X(00)00259-4