Novel transcripts encoding secreted forms of feline CD80 and CD86 costimulatory molecules

Engagement of costimulatory molecules such as CD28 or CD152 (CTLA4) on T cells by CD80 (B7-1) or CD86 (B7-2) dictates the nature of T cell-mediated immune responses. We previously reported the discovery of naturally occurring forms of canine CD80 and CD86 mRNAs which encode secreted CD80 and CD86 mo...

Ausführliche Beschreibung