Discovery and design of novel and selective vasopressin and oxytocin agonists and antagonists: the role of bioassays

Synthetic oxytocin and vasopressin agonists and antagonists have become important tools for research and were instrumental in the identification of the four known receptor subtypes, V1a, V2, V1b (V3) and oxytocin, of these peptide hormones. However, the relative lack of receptor selectivity, particu...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Experimental physiology 2000-03, Vol.85 (s1), p.7s-18s
Hauptverfasser:	Chan, W. Y., Wo, Nga Ching, Stoev, Stoytcho, Cheng, Ling Ling, Manning, Maurice
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Antihypertensive Agents - pharmacology Biological Assay - trends Drug Design Oxytocin - agonists Oxytocin - antagonists & inhibitors Oxytocin - chemistry Vasopressins - agonists Vasopressins - antagonists & inhibitors Vasopressins - chemistry
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!