Cytokine production induced by binding and processing of calcium oxalate crystals in cultured macrophages

Deposition of calcium oxalate (CaOx) crystals in the renal interstitium is common in humans with primary oxalosis and secondary hyperoxaluria, as well as in kidneys of rats with CaOx nephrolithiasis. In vivo, macrophages and multinucleated giant cells mostly encapsulate these crystals. To investigat...

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Veröffentlicht in:	American journal of kidney diseases 2001-08, Vol.38 (2), p.331-338
Hauptverfasser:	de Water, Ruud, Leenen, Pieter J.M., Noordermeer, Cindy, Nigg, Alex L., Houtsmuller, Adriaan B., Kok, Dirk J., Schr[ouml ]der, Fritz H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Calcium Oxalate - metabolism Cell Death Cells, Cultured Crystallization Interleukin-6 - biosynthesis Macrophages - cytology Macrophages - metabolism Medical sciences Mice Microscopy, Confocal Nephrology. Urinary tract diseases Phagocytosis Tumor Necrosis Factor-alpha - biosynthesis Urinary lithiasis
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