Angiostatic effects of suramin analogs in vitro

Suramin analogs are polyanionic naphthylureas structurally related to suramin, an antitumor agent with a narrow therapeutic window. The angiostatic activities of suramin and 16 suramin analogs were investigated using an easily quantifiable in vitro angiogenesis system. In addition, the antiprolifera...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Anti-cancer drugs 2000-02, Vol.11 (2), p.69-77
Hauptverfasser:	Firsching-Hauck, Angela, Nickel, Peter, Yahya, Claudia, Wandt, Carla, Kulik, Renate, Simon, Nicola, Zink, Martina, Nehls, Volker, Allolio, Bruno
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiogenesis Inhibitors - chemistry Angiogenesis Inhibitors - pharmacology angiostatic agents Animals Antineoplastic Agents - chemistry Antineoplastic Agents - pharmacology Cell Division - drug effects Cell Line Dose-Response Relationship, Drug Endothelium, Vascular - cytology Endothelium, Vascular - drug effects HT29 Cells - drug effects Humans naphthylureas Structure-Activity Relationship suramin Suramin - analogs & derivatives Suramin - chemistry Suramin - pharmacology Swine Tumor Cells, Cultured
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!