Interleukin 6 activates androgen receptor-mediated gene expression through a signal transducer and activator of transcription 3-dependent pathway in LNCaP prostate cancer cells

Interleukin 6 (IL-6) is a cytokine that regulates not only immune and inflammatory responses but also the growth of some tumors, including prostate carcinomas. IL-6 signals through Janus kinase, signal transducer and activator of transcription 3 (STAT3), and mitogen-activated protein kinase and is a...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 2000-04, Vol.60 (8), p.2132-2135
Hauptverfasser:	TAOSHENG CHEN, LI HUA WANG, FARRAR, W. L
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Carrier Proteins - genetics Carrier Proteins - metabolism Disease Progression DNA-Binding Proteins - antagonists & inhibitors DNA-Binding Proteins - genetics DNA-Binding Proteins - metabolism Enzyme Activation - drug effects Gene Expression Regulation, Neoplastic - drug effects Genes, Reporter - genetics Humans Interleukin-6 - antagonists & inhibitors Interleukin-6 - pharmacology Intracellular Signaling Peptides and Proteins Janus Kinase 2 Male Medical sciences Metribolone - pharmacology Mitogen-Activated Protein Kinases - antagonists & inhibitors Mitogen-Activated Protein Kinases - metabolism Mutation - genetics Nephrology. Urinary tract diseases Prostatic Neoplasms - enzymology Prostatic Neoplasms - genetics Prostatic Neoplasms - metabolism Protein Binding - drug effects Protein-Tyrosine Kinases - antagonists & inhibitors Protein-Tyrosine Kinases - metabolism Proteins - genetics Proteins - metabolism Proto-Oncogene Proteins Receptors, Androgen - metabolism Repressor Proteins Response Elements - genetics Signal Transduction - drug effects STAT3 Transcription Factor Suppressor of Cytokine Signaling 1 Protein Suppressor of Cytokine Signaling Proteins Testosterone Congeners - pharmacology Trans-Activators - antagonists & inhibitors Trans-Activators - genetics Trans-Activators - metabolism Transcriptional Activation Transfection Tumor Cells, Cultured Tumors of the urinary system Urinary tract. Prostate gland
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!