A spectrophotometric-partial least squares (PLS-1) method for the simultaneous determination of furosemide and amiloride hydrochloride in pharmaceutical formulations

A numerical method, based on the use of spectrophotometric data coupled to PLS-1 multivariate calibration, is reported for the simultaneous determination of furosemide and amiloride hydrochloride in synthetic samples and commercial tablets. The method was applied in the concentration ranges of 8.0–1...

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Veröffentlicht in:Journal of pharmaceutical and biomedical analysis 2001-10, Vol.26 (3), p.443-451
Hauptverfasser: Ferraro, Mónica C.F., Castellano, Patricia M., Kaufman, Teodoro S.
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Sprache:eng
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