The role of iNOS in wound healing

Background. We have previously shown that the blockade of nitric oxide (NO) synthesis impairs wound healing, in particular collagen synthesis. Conversely, impaired wound healing is accompanied by decreased wound NO synthesis. Fibroblast collagen synthesis, proliferation, and fibroblast-mediated matr...

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Veröffentlicht in:	Surgery 2001-08, Vol.130 (2), p.225-229
Hauptverfasser:	Shi, Han Ping, Most, Daniel, Efron, David T., Tantry, U., Fischel, M.H., Barbul, Adrian
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Cell Division - physiology Cells, Cultured Collagen - biosynthesis Fibroblasts - cytology Fibroblasts - drug effects Fibroblasts - enzymology Male Medical sciences Mice Mice, Inbred C57BL Mice, Knockout Miscellaneous Nitric Oxide Donors Nitric Oxide Synthase - genetics Nitric Oxide Synthase - metabolism Nitric Oxide Synthase Type II Penicillamine - analogs & derivatives Penicillamine - pharmacology Skin - cytology Traumas. Diseases due to physical agents Wound Healing - physiology
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