Chemical neuroanatomy of the basal ganglia — normal and in Parkinson's disease
This synopsis clearly shows that the investigations eventually resulting in the development of the new concept about the functional neurotransmitter organisation of the basal ganglia represents an important achievement in neuroscience research. This concept combines knowledge gained from studies on...
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| Veröffentlicht in: | Journal of chemical neuroanatomy 2001-07, Vol.22 (1), p.3-12 |
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| container_title | Journal of chemical neuroanatomy |
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| creator | Hornykiewicz, Oleh |
| description | This synopsis clearly shows that the investigations eventually resulting in the development of the new concept about the functional neurotransmitter organisation of the basal ganglia represents an important achievement in neuroscience research. This concept combines knowledge gained from studies on the neurophysiology, the functional neuroanatomy and the chemical brain topography, both in laboratory experiments and in normal and diseased human brain. The insights into the functioning of the human brain gained from biochemical-neuroanatomical studies in patients dying with neurological disorders, especially PD, confirm the old medical adage that 'pathology is the greatest teacher of function'. |
| doi_str_mv | 10.1016/S0891-0618(01)00100-4 |
| format | Article |
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| identifier | ISSN: 0891-0618 |
| ispartof | Journal of chemical neuroanatomy, 2001-07, Vol.22 (1), p.3-12 |
| issn | 0891-0618 1873-6300 |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | Basal Ganglia - metabolism Basal Ganglia - pathology Basal Ganglia - physiopathology Brain Chemistry - physiology Dopamine - metabolism gamma-Aminobutyric Acid - metabolism Glutamic Acid - metabolism Humans Neurons - metabolism Neurons - pathology Neuropeptides - metabolism Parkinson Disease - metabolism Parkinson Disease - pathology Parkinson Disease - physiopathology |
| title | Chemical neuroanatomy of the basal ganglia — normal and in Parkinson's disease |
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