Susceptibility to critical illness: reserve, response and therapy
Risk of critical illness is determined both by genetic and environmental influences, particularly those relating to infectious and cardiovascular diseases. Physiologically-based scoring systems cannot measure prior risk because they do not quantify physiological reserve independently of the acute il...
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| Veröffentlicht in: | Intensive care medicine 2000-02, Vol.26 Suppl 1 (S1), p.S57-S063 |
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| container_title | Intensive care medicine |
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| creator | Bion, J F |
| description | Risk of critical illness is determined both by genetic and environmental influences, particularly those relating to infectious and cardiovascular diseases. Physiologically-based scoring systems cannot measure prior risk because they do not quantify physiological reserve independently of the acute illness. Genetic profiling could be useful for risk assessment. Early detection of critical illness involves identifying physiological 'triggers' for referral; this requires the education of nursing and medical staff in their significance. Analysis of the relationship between risk factors and interventions may need complex modelling techniques. Therapeutic strategies depend on the nature of the underlying problem: the most useful are likely to be those which enhance tissue oxygen delivery and resistance to infection. |
| doi_str_mv | 10.1007/s001340051120 |
| format | Article |
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| fulltext | fulltext |
| identifier | ISSN: 0342-4642 |
| ispartof | Intensive care medicine, 2000-02, Vol.26 Suppl 1 (S1), p.S57-S063 |
| issn | 0342-4642 1432-1238 |
| language | eng |
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| source | MEDLINE; Springer Nature - Complete Springer Journals |
| subjects | Cardiovascular diseases Clinical outcomes Critical Care Critical Illness Disease Disease Susceptibility Education Emergency medical care Hospitals Humans Illnesses infection Intensive care intervention Mortality Oxygen Patients Physiology Risk assessment Risk Factors Severity of Illness Index Variables |
| title | Susceptibility to critical illness: reserve, response and therapy |
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