Exploiting anthracycline scaffold for designing DNA-targeting agents
One possible approach to controlling the effects of pathogenic genes is to control their expression at the transcription level. However, only a small number of high-affinity DNA-binding agents are currently available, and their sequence selectivity is limited. Clearly, there is an urgent need to dev...
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Veröffentlicht in: | Methods in Enzymology 2001, Vol.340, p.529-555 |
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