Should women at increased risk for breast and ovarian cancer be randomized to prophylactic surgery? An ethical and empirical assessment

More information is needed about the relative effectiveness of prophylactic surgery, chemoprevention, and surveillance in reducing breast and ovarian cancer risk in women with an inherited susceptibility mutation. We assessed practical and ethical barriers to conducting randomized clinical trials (R...

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Veröffentlicht in:	Journal of women's health & gender-based medicine 2000-04, Vol.9 (3), p.223-233
Hauptverfasser:	Tambor, E S, Bernhardt, B A, Geller, G, Helzlsouer, K J, Doksum, T, Holtzman, N A
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Bioethics Breast Neoplasms - genetics Breast Neoplasms - prevention & control Breast Neoplasms - psychology Breast Neoplasms - surgery Data Collection Ethics, Medical Female Genetic Predisposition to Disease Humans Ovarian Neoplasms - genetics Ovarian Neoplasms - prevention & control Ovarian Neoplasms - psychology Ovarian Neoplasms - surgery Patient Selection Randomized Controlled Trials as Topic Risk Factors Women's Health
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