Immunohistochemical analysis still has a limited role in the diagnosis of malignant mesothelioma: A study of thirteen antibodies

To identify the most accurate and useful panel to diagnose mesothelioma, we immunostained sections from 112 mesotheliomas, 18 adenocarcinomas, and 11 reactive pleural specimens with 13 antibodies. Positive results for mesotheliomas, adenocarcinomas, and reactive pleura, respectively, were CAM5.2, 11...

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Veröffentlicht in:	American journal of clinical pathology 2001-08, Vol.116 (2), p.253-262
Hauptverfasser:	ROBERTS, Fiona, HARPER, Christina M, DOWNIE, Ian, BURNETT, Rodney A
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - chemistry Adenocarcinoma - diagnosis Antigens, Surface - analysis Biological and medical sciences Biomarkers Biomarkers, Tumor - analysis Calbindin 2 Carcinoembryonic Antigen - analysis Diagnosis, Differential Glycoproteins - analysis Humans Hyaluronan Receptors - analysis Immunohistochemistry Investigative techniques, diagnostic techniques (general aspects) Keratins - analysis Lewis X Antigen - analysis Medical sciences Mesothelioma - chemistry Mesothelioma - diagnosis Miscellaneous. Technology Mucin-1 - analysis Neoplasm Metastasis Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Peritoneal Neoplasms - chemistry Peritoneal Neoplasms - diagnosis Pleural Neoplasms - chemistry Pleural Neoplasms - diagnosis Receptor, Platelet-Derived Growth Factor beta - analysis S100 Calcium Binding Protein G - analysis Thrombomodulin - analysis Tumor Suppressor Protein p53 - analysis Vimentin - analysis
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