Predicting sequences and structures of MHC-binding peptides: a computational combinatorial approach

Peptides bound to MHC molecules on the surface of cells convey critical information about the cellular milieu to immune system T cells. Predicting which peptides can bind an MHC molecule, and understanding their modes of binding, are important in order to design better diagnostic and therapeutic age...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Journal of computer-aided molecular design 2001-06, Vol.15 (6), p.573-586
Hauptverfasser:	Zen, J, Treutlein, H R, Rudy, G B
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Amino acids Autoimmune diseases Combinatorial Chemistry Techniques Immune system Major Histocompatibility Complex Markov Chains Models, Molecular Peptides Peptides - chemistry Peptides - metabolism Protein Conformation Proteins
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!