p-Cresol Sulfate Is the Dominant Component of Urinary Myelin Basic Protein Like Material

Multiple sclerosis (MS) is clinically heterogeneous and has an uncertain natural history. A high priority for more effective treatment of MS is an objective and feasible laboratory test for predicting the disease's course and response to treatments. Urinary myelin basic protein (MBP)-like mater...

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Veröffentlicht in:	Archives of biochemistry and biophysics 2000-05, Vol.377 (1), p.9-21
Hauptverfasser:	Cao, Ligong, Kirk, Marion C., Coward, Lori U., Jackson, Patricia, Whitaker, John N.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetic Acid - metabolism Amino Acids - analysis Ammonium Hydroxide Chromatography, High Pressure Liquid Cresols - analysis Cresols - chemistry Cresols - immunology Cresols - urine Cross Reactions - immunology Epitopes - chemistry Epitopes - immunology Female HPLC Humans Hydroxides - metabolism Isomerism Magnetic Resonance Spectroscopy Male Mass Spectrometry Middle Aged Molecular Weight multiple sclerosis Multiple Sclerosis - diagnosis Multiple Sclerosis - immunology Multiple Sclerosis - urine myelin basic protein Myelin Basic Protein - chemistry Myelin Basic Protein - immunology Myelin Basic Protein - isolation & purification Myelin Basic Protein - urine nuclear magnetic resonance spectroscopy p-cresol sulfate Polymers - metabolism Radioimmunoassay Sequence Analysis, Protein Sulfates - analysis Sulfuric Acid Esters - analysis Sulfuric Acid Esters - chemistry Sulfuric Acid Esters - immunology Sulfuric Acid Esters - urine Tetraethylammonium - metabolism urine
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