A prospective randomised controlled study of patient‐controlled propofol sedation in phobic dental patients
The safety and effectiveness of patient‐controlled propofol sedation was prospectively assessed in 18 healthy, phobic dental patients. Using a randomised, crossover design each patient received two sessions of equivalent dental treatment under patient‐controlled or clinician‐controlled propofol seda...
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| Veröffentlicht in: | Anaesthesia 2000-04, Vol.55 (4), p.327-333 |
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| creator | Girdler, N. M. Rynn, D. Lyne, J. P. Wilson, K. E. |
| description | The safety and effectiveness of patient‐controlled propofol sedation was prospectively assessed in 18 healthy, phobic dental patients. Using a randomised, crossover design each patient received two sessions of equivalent dental treatment under patient‐controlled or clinician‐controlled propofol sedation. The patient‐controlled technique used 29.8% less drug (time‐weighted dose) than the clinician‐controlled method (p = 0.011). There was a high correlation between number of demands and number of doses actually infused during the patient‐controlled technique (r = 0.99, p |
| doi_str_mv | 10.1046/j.1365-2044.2000.01279.x |
| format | Article |
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Patient‐controlled sedation produced a greater reduction in dental and general anxiety compared with clinician‐controlled sedation, but the difference did not reach statistical significance. Three times the number of patients expressed a preference for the patient‐controlled, compared with the clinician‐controlled, technique. Patient‐controlled sedation provides safe and acceptable intra‐operative anxiolysis for phobic dental patients, but with reduced propofol dosage.</description><identifier>ISSN: 0003-2409</identifier><identifier>EISSN: 1365-2044</identifier><identifier>DOI: 10.1046/j.1365-2044.2000.01279.x</identifier><identifier>PMID: 10781117</identifier><identifier>CODEN: ANASAB</identifier><language>eng</language><publisher>Oxford: Blackwell Science Ltd</publisher><subject>Adult ; Anaesthetics, intravenous: propofol ; Biological and medical sciences ; Conscious Sedation - methods ; Cross-Over Studies ; Dentistry, Operative ; Drug Administration Schedule ; Female ; Humans ; Hypnotics and Sedatives - therapeutic use ; Hypnotics. Sedatives ; Male ; Medical sciences ; Middle Aged ; Neuropharmacology ; Pharmacology. Drug treatments ; Phobic Disorders - drug therapy ; Propofol - therapeutic use ; Prospective Studies ; Psychology. Psychoanalysis. 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M.</creatorcontrib><creatorcontrib>Rynn, D.</creatorcontrib><creatorcontrib>Lyne, J. P.</creatorcontrib><creatorcontrib>Wilson, K. E.</creatorcontrib><title>A prospective randomised controlled study of patient‐controlled propofol sedation in phobic dental patients</title><title>Anaesthesia</title><addtitle>Anaesthesia</addtitle><description>The safety and effectiveness of patient‐controlled propofol sedation was prospectively assessed in 18 healthy, phobic dental patients. Using a randomised, crossover design each patient received two sessions of equivalent dental treatment under patient‐controlled or clinician‐controlled propofol sedation. The patient‐controlled technique used 29.8% less drug (time‐weighted dose) than the clinician‐controlled method (p = 0.011). There was a high correlation between number of demands and number of doses actually infused during the patient‐controlled technique (r = 0.99, p < 0.001). Clinically, the level of sedation was lighter and the degree of operator satisfaction was higher with patient‐controlled sedation. Blood pressure and arterial oxygen saturation showed minimal changes and remained within normal ranges during both techniques. Patient‐controlled sedation produced a greater reduction in dental and general anxiety compared with clinician‐controlled sedation, but the difference did not reach statistical significance. Three times the number of patients expressed a preference for the patient‐controlled, compared with the clinician‐controlled, technique. Patient‐controlled sedation provides safe and acceptable intra‐operative anxiolysis for phobic dental patients, but with reduced propofol dosage.</description><subject>Adult</subject><subject>Anaesthetics, intravenous: propofol</subject><subject>Biological and medical sciences</subject><subject>Conscious Sedation - methods</subject><subject>Cross-Over Studies</subject><subject>Dentistry, Operative</subject><subject>Drug Administration Schedule</subject><subject>Female</subject><subject>Humans</subject><subject>Hypnotics and Sedatives - therapeutic use</subject><subject>Hypnotics. Sedatives</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Neuropharmacology</subject><subject>Pharmacology. Drug treatments</subject><subject>Phobic Disorders - drug therapy</subject><subject>Propofol - therapeutic use</subject><subject>Prospective Studies</subject><subject>Psychology. Psychoanalysis. Psychiatry</subject><subject>Psychopharmacology</subject><subject>Sedation: patient‐controlled</subject><subject>Self Administration</subject><subject>Surgery: dental</subject><issn>0003-2409</issn><issn>1365-2044</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2000</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkc1O3DAUha0KBFPKK1ReVIhNgq-dxJ4N0ghRioTaTbu2HPtGzcgTp3EGmB2PwDP2SXCYKWWFWPlK5zu-P4cQCiwHVlRnyxxEVWacFUXOGWM5Ay7n-f0HMnsR9sgsKSLjBZsfko8xLlmiFKgDcghMKgCQM7Ja0H4IsUc7trdIB9O5sGojOmpDNw7B-1TGce02NDS0N2OL3fj34fGVmvx9aIKnyZX00NG2o_3vULeWukQb_88XP5H9xviIx7v3iPz6evnz4lt28-Pq-mJxk9mSyXkmy1qYhqNs0FSuRFc4XtdlwVUBwlWIijkFjXMS0x6Fs467ipUCGAchqlockZPtv2m2P2uMo047WfTedBjWUUtgFcgSEnj6JghKSsUFcJFQtUVtulccsNH90K7MsNHA9JSKXurp-Ho6vp5S0c-p6Ptk_bzrsq5X6F4ZtzEk4MsOMNEa36QYbBv_c4LD_Hna8y1213rcvLu_XnxfXE6leAKWoKrh</recordid><startdate>200004</startdate><enddate>200004</enddate><creator>Girdler, N. M.</creator><creator>Rynn, D.</creator><creator>Lyne, J. P.</creator><creator>Wilson, K. E.</creator><general>Blackwell Science Ltd</general><general>Blackwell</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>7U7</scope><scope>C1K</scope><scope>H94</scope><scope>7X8</scope></search><sort><creationdate>200004</creationdate><title>A prospective randomised controlled study of patient‐controlled propofol sedation in phobic dental patients</title><author>Girdler, N. M. ; Rynn, D. ; Lyne, J. P. ; Wilson, K. E.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5079-75b3af2e7fea6d5ed4d2bb5428413d6ee80d81fdd7e7814dcd2d60531021336b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2000</creationdate><topic>Adult</topic><topic>Anaesthetics, intravenous: propofol</topic><topic>Biological and medical sciences</topic><topic>Conscious Sedation - methods</topic><topic>Cross-Over Studies</topic><topic>Dentistry, Operative</topic><topic>Drug Administration Schedule</topic><topic>Female</topic><topic>Humans</topic><topic>Hypnotics and Sedatives - therapeutic use</topic><topic>Hypnotics. Sedatives</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Neuropharmacology</topic><topic>Pharmacology. Drug treatments</topic><topic>Phobic Disorders - drug therapy</topic><topic>Propofol - therapeutic use</topic><topic>Prospective Studies</topic><topic>Psychology. Psychoanalysis. Psychiatry</topic><topic>Psychopharmacology</topic><topic>Sedation: patient‐controlled</topic><topic>Self Administration</topic><topic>Surgery: dental</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Girdler, N. M.</creatorcontrib><creatorcontrib>Rynn, D.</creatorcontrib><creatorcontrib>Lyne, J. P.</creatorcontrib><creatorcontrib>Wilson, K. 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E.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A prospective randomised controlled study of patient‐controlled propofol sedation in phobic dental patients</atitle><jtitle>Anaesthesia</jtitle><addtitle>Anaesthesia</addtitle><date>2000-04</date><risdate>2000</risdate><volume>55</volume><issue>4</issue><spage>327</spage><epage>333</epage><pages>327-333</pages><issn>0003-2409</issn><eissn>1365-2044</eissn><coden>ANASAB</coden><abstract>The safety and effectiveness of patient‐controlled propofol sedation was prospectively assessed in 18 healthy, phobic dental patients. Using a randomised, crossover design each patient received two sessions of equivalent dental treatment under patient‐controlled or clinician‐controlled propofol sedation. The patient‐controlled technique used 29.8% less drug (time‐weighted dose) than the clinician‐controlled method (p = 0.011). There was a high correlation between number of demands and number of doses actually infused during the patient‐controlled technique (r = 0.99, p < 0.001). Clinically, the level of sedation was lighter and the degree of operator satisfaction was higher with patient‐controlled sedation. Blood pressure and arterial oxygen saturation showed minimal changes and remained within normal ranges during both techniques. Patient‐controlled sedation produced a greater reduction in dental and general anxiety compared with clinician‐controlled sedation, but the difference did not reach statistical significance. Three times the number of patients expressed a preference for the patient‐controlled, compared with the clinician‐controlled, technique. Patient‐controlled sedation provides safe and acceptable intra‐operative anxiolysis for phobic dental patients, but with reduced propofol dosage.</abstract><cop>Oxford</cop><pub>Blackwell Science Ltd</pub><pmid>10781117</pmid><doi>10.1046/j.1365-2044.2000.01279.x</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
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| source | Wiley Online Library - AutoHoldings Journals; MEDLINE; Wiley Free Archive; EZB-FREE-00999 freely available EZB journals |
| subjects | Adult Anaesthetics, intravenous: propofol Biological and medical sciences Conscious Sedation - methods Cross-Over Studies Dentistry, Operative Drug Administration Schedule Female Humans Hypnotics and Sedatives - therapeutic use Hypnotics. Sedatives Male Medical sciences Middle Aged Neuropharmacology Pharmacology. Drug treatments Phobic Disorders - drug therapy Propofol - therapeutic use Prospective Studies Psychology. Psychoanalysis. Psychiatry Psychopharmacology Sedation: patient‐controlled Self Administration Surgery: dental |
| title | A prospective randomised controlled study of patient‐controlled propofol sedation in phobic dental patients |
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