T311—An Anti-Tyrosinase Monoclonal Antibody for the Detection of Melanocytic Lesions in Paraffin Embedded Tissues

Tyrosinase is a key enzyme in melanin biosynthesis and represents a marker of melanocytic differentiation. We previously generated T311, a murine monoclonal antibody to the tyrosinase recombinant protein. This study was performed to evaluate T311 as a diagnostic immunohistochemical reagent for use o...

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Veröffentlicht in:	Pathology, research and practice research and practice, 2000, Vol.196 (4), p.235-242
Hauptverfasser:	Jungbluth, Achim A., Iversen, Kristin, Coplan, Keren, Kolb, Denise, Stockert, Elisabeth, Chen, Yao-Tseng, Old, Lloyd J., Busam, Klaus
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies, Monoclonal Humans Immunohistochemistry Melanocyte-associated markers Melanocytes - enzymology Melanocytes - pathology Melanoma - enzymology Melanoma - pathology Monophenol Monooxygenase - analysis Monophenol Monooxygenase - immunology Neoplasms - enzymology Neoplasms - pathology Paraffin Embedding Skin - enzymology Skin - pathology Skin Neoplasms - enzymology Skin Neoplasms - pathology T311 Tyrosinase
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