Stromal Cell-Derived Factor-1 as a Chemoattractant for Follicular Center Lymphoma B Cells

Background: Follicular center lymphoma displays widespread lymph node involvement at diagnosis. The chemoattractants that control the locomotion of follicular center lymphoma B cells have not been established. Stromal cell-derived factor-1 (SDF-1) is a CXC-class chemokine that enhances the migration...

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Veröffentlicht in:	JNCI : Journal of the National Cancer Institute 2000-04, Vol.92 (8), p.628-635
Hauptverfasser:	Corcione, Anna, Ottonello, Luciano, Tortolina, Giuseppe, Facchetti, Paola, Airoldi, Irma, Guglielmino, Roberta, Dadati, Patrizia, Truini, Mauro, Sozzani, Silvano, Dallegri, Franco, Pistoia, Vito
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies, Monoclonal - pharmacology B-Lymphocytes - metabolism B-Lymphocytes - physiology Base Sequence Biological and medical sciences CD40 Antigens - immunology CD40 Antigens - physiology Chemokine CXCL12 Chemokines, CXC - genetics Chemokines, CXC - pharmacology Chemotactic Factors - pharmacology Chemotaxis Gene Expression Hematologic and hematopoietic diseases Humans Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Lymph Nodes - metabolism Lymphoma, Follicular - genetics Lymphoma, Follicular - metabolism Medical sciences Molecular Sequence Data Receptors, CXCR4 - metabolism Receptors, Interleukin-4 - immunology Receptors, Interleukin-4 - physiology
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