Defensins are dominant HLA-DR-associated self-peptides from CD34− peripheral blood mononuclear cells of different tumor patients (plasmacytoma, chronic myeloid leukemia)

The HLA-DR-associated peptides from peripheral blood mononuclear cells of 2 patients with plasmacytoma and 1 with chronic myeloid leukemia were isolated, identified, and compared. Several were identified as derivatives of the defensin family. Defensins (or human neutrophil peptides [HNP]) are antimi...

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